Gonçalves Pereira Rita, Branco Joana, Narciso Rocha Filipa, Figueiredo Catarina, Costa Ana Rita, Santos Silva João, Reis João Eurico, Calvinho Paulo
Thoracic Surgery Unit of the Department of Cardiothoracic Surgery, Centro Hospitalar Lisboa Central; Department of General Surgery, Centro Hospitalar Barreiro-Montijo, Portugal.
Thoracic Surgery Unit of the Department of Cardiothoracic Surgery, Centro Hospitalar Lisboa Central; Department of Pneumology, Hospital Beatriz Ângelo, Portugal.
Port J Card Thorac Vasc Surg. 2021 Nov 7;28(3):25-32. doi: 10.48729/pjctvs.191.
The risk stratification of lung resection is fundamentally based on the results of pulmonary function tests. In patients considered to be at risk, major surgery is generally denied, opting for potentially less curative therapies.
To evaluate the postoperative outcomes of major lung surgery in a group of patients deemed high risk.
We performed a retrospective review of clinical records of all patients submitted to lobectomy, bilobectomy or pneumonectomy in a 3-year period in a reference Thoracic Surgery Unit. The patients were then divided in two groups: group A composed of patients with normal preoperative pulmonary function and group B which included patients with impaired lung function, defined as FEV1 and/or DLCO ≤60%.
A total of 234 patients were included, 181 (77.4%) in group A and 53 (22.6%) in group B. In group B, patients had more smoking habits, were more often associated with chronic obstructive pulmonary disease and were also more frequently submitted to thoracotomy. When surgery was motivated by primary lung cancer this group had a more advanced clinical stage of the disease. In the postoperative period, these patients had longer hospital stay, longer chest drainage time and greater need for oxygen therapy at home, however, no statistically significant difference was noted in morbidity or mortality.
Major thoracic surgery can be safely performed in selected patients considered to be high risk for resection by pulmonary function tests. A potentially curative surgery should not be denied based on respiratory function tests alone.
肺切除术的风险分层基本上基于肺功能测试结果。对于被认为有风险的患者,通常不进行大手术,而是选择疗效可能较差的治疗方法。
评估一组被认为高风险患者进行大肺手术的术后结果。
我们对一家参考胸外科单位在3年期间接受肺叶切除术、双肺叶切除术或全肺切除术的所有患者的临床记录进行了回顾性分析。然后将患者分为两组:A组由术前肺功能正常的患者组成,B组包括肺功能受损的患者,定义为第一秒用力呼气容积(FEV1)和/或一氧化碳弥散量(DLCO)≤60%。
共纳入234例患者,A组181例(77.4%),B组53例(22.6%)。在B组中,患者吸烟习惯更多,更常合并慢性阻塞性肺疾病,也更常接受开胸手术。当手术由原发性肺癌引起时,该组疾病的临床分期更晚。术后,这些患者住院时间更长,胸腔引流时间更长,在家中对氧疗的需求更大,然而,在发病率或死亡率方面未发现统计学上的显著差异。
对于经肺功能测试被认为是高风险切除的特定患者,可以安全地进行大胸外科手术。不应仅基于呼吸功能测试而拒绝可能治愈的手术。