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[治疗性低温诱导的QT间期延长和“尖端扭转型”室性心动过速]

[Therapeutic hypothermia-induced QT prolongation and “torsade de pointes” ventricular tachycardia].

作者信息

Tomcsányi János, Arányi Péter, Arabadzisz Hrisula

机构信息

1 Budai Irgalmasrendi Kórház, Kardiológia Budapest, Árpád fejedelem u. 7., 1023 Magyarország.

出版信息

Orv Hetil. 2022 Mar 27;163(13):523-526. doi: 10.1556/650.2022.32367.

Abstract

The authors describe the course of disease in a 44-year-old female patient with autoimmune disease. After successful resuscitation following unexpected hospital ventricular fibrillation, the patient remained in a comatose state and therefore received therapeutic hypothermia. Hypothermic treatment resulted in significant QT prolongation and "torsade de pointes" ventricular tachycardia. The probable cause of arrhythmia is the QT prolongation caused by the hypothermia and the consequential early afterdepolarization and triggered activity. The authors draw attention to the fact that - to the best of our knowledge - milder hypothermia is recommended within the preset hypothermic range. Orv Hetil. 2022; 163(13): 523-526.

摘要

作者描述了一名患有自身免疫性疾病的44岁女性患者的病程。在因意外的医院内室颤成功复苏后,患者仍处于昏迷状态,因此接受了治疗性低温治疗。低温治疗导致显著的QT间期延长和尖端扭转型室性心动过速。心律失常的可能原因是低温引起的QT间期延长以及随之而来的早期后除极和触发活动。作者提请注意这样一个事实,即据我们所知,在预设的低温范围内建议采用较温和的低温。《匈牙利医学周报》。2022年;163(13):523 - 526。

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