Targeting anxiety and senescence with senolytics.
作者信息
Raffaele Marco, Vinciguerra Manlio
机构信息
International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
Department of Translational Stem Cell Biology, Research Institute of the Medical University of Varna, Varna, Bulgaria.
出版信息
Aging (Albany NY). 2022 Mar 27;14(6):2438-2439. doi: 10.18632/aging.203985.
Abstract
摘要
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本文引用的文献
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The costs and benefits of senotherapeutics for human health.衰老治疗对人类健康的成本和收益。
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Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects.孤啡肽/阿片样物质 FQ 受体（NOP）选择性配体 MCOPPB 具有抗焦虑和衰老细胞清除作用。
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Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin.衰老细胞清除剂达沙替尼 + 槲皮素加剧肥胖和年龄相关的肝疾病进展。
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Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.肥胖诱导的细胞衰老引发焦虑并损害神经发生。
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