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发展中国家采用空肠游离皮瓣重建术的全咽喉颈段食管切除术:越南的一例病例报告

Total Pharyngo-Laryngo-Cervical-Esophagectomy with Jejunal Free Flap Reconstruction in a Developing Country: A Case Report from Vietnam.

作者信息

Van Binh Pham, Tien Hung Nguyen, Van Nha Hoang, Viet Dung Dang, Thanh Hoa Nguyen Thi

机构信息

Abdominal Surgery Department 1 and Robotic Surgery Center, Vietnam National Cancer Hospital, Hanoi, Vietnam.

Department of Otolaryngology - Head and Neck Surgery, Vietnam National Cancer Hospital, Hanoi, Vietnam.

出版信息

Am J Case Rep. 2022 Mar 28;23:e934974. doi: 10.12659/AJCR.934974.

Abstract

BACKGROUND Esophageal invasion in hypopharyngeal cancer is an uncommon lesion and has a poor prognosis. Total pharyngo-laryngo-esophagectomy is the most effective treatment option. Reconstruction of the gastrointestinal tract in the same period of surgery is required. There are many different options, such as pedicle flap, gastric pull-up, pedicled transverse colon flaps, and free flap. In cases where only cervical esophagectomy is required, with benefits for patients, jejunal free flap is the first choice to reconstruct the esophagus. However, the extensive surgical resection requires interdisciplinary collaboration among surgical specialities, which is not always available. CASE REPORT A 52-year-old male patient came to us with a chief concern of dysphagia, which first appeared 3 months ago. Rigid fiberoptic and direct laryngoscopes indirectly observed the tumor at the posterior wall; it had passed the esophagus opening and infiltrated to the cervical esophagus, with the rightmost part spread into the right pyriform sinus. Histopathology studies of the tumor showed a squamous cell carcinoma. The patient underwent total pharyngo-laryngo-cervico-esophagectomy, reconstructed with a jejunal free flap, and adjuvant radiation therapy after surgery. At follow-up 1 year after surgery, the patient was significantly recovery with no signs of tumor recurrence, no difficulties of oral intake, and his speech was restored by electrolarynx. CONCLUSIONS We reported the case of a patient with hypopharyngeal cancer who underwent total pharyngo-laryngo-cervico-esophagectomy and esophagus reconstruction using a jejunal free flap, performed for the first time in Vietnam. As expected, with good oncological and functional results, the degree of invasiveness and sequelae of the surgery can be well tolerated.

摘要

背景 下咽癌侵犯食管是一种罕见病变,预后较差。全下咽-喉-食管切除术是最有效的治疗选择。手术同期需要重建胃肠道。有许多不同的选择,如带蒂皮瓣、胃上提术、带蒂横结肠皮瓣和游离皮瓣。在仅需行颈段食管切除术且对患者有益的情况下,空肠游离皮瓣是重建食管的首选。然而,广泛的手术切除需要外科各专业之间的跨学科协作,而这种协作并非总能实现。病例报告 一名52岁男性患者因吞咽困难前来就诊,吞咽困难于3个月前首次出现。硬质纤维喉镜和直接喉镜间接观察到肿瘤位于后壁;肿瘤已穿过食管开口并浸润至颈段食管,最右侧部分蔓延至右侧梨状窝。肿瘤的组织病理学研究显示为鳞状细胞癌。该患者接受了全下咽-喉-颈段食管切除术,采用空肠游离皮瓣重建,并在术后接受辅助放疗。术后1年随访时,患者恢复良好,无肿瘤复发迹象,经口进食无困难,通过电子喉恢复了说话能力。结论 我们报告了一例下咽癌患者的病例,该患者接受了全下咽-喉-颈段食管切除术,并采用空肠游离皮瓣进行食管重建,此手术在越南尚属首次。正如预期的那样,手术取得了良好的肿瘤学和功能效果,手术的侵袭程度和后遗症患者均可良好耐受。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaec/8973398/9def8cdbc62a/amjcaserep-23-e934974-g001.jpg

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