Department of Otolaryngology-Head and Neck Surgery, University of Washington, 1959 Northeast Pacific Street, Seattle, WA 98195, USA.
Department of Otolaryngology-Head and Neck Surgery, University of Washington, 1959 Northeast Pacific Street, Seattle, WA 98195, USA.
Surg Clin North Am. 2022 Apr;102(2):309-324. doi: 10.1016/j.suc.2021.12.007. Epub 2022 Mar 5.
Oral cavity cancer represents a heterogeneous group of cancers with unique etiologic, diagnostic, and treatment considerations based on the subsite. While decreases in smoking have resulted in the development of fewer oral cavity cancers, the incidence remains high in certain geographic areas. History and physical examination, as well as tissue biopsy, are key to diagnosis. Although surgical resection is the primary treatment modality for oral cavity cancer, the optimal treatment plan for a patient is an individualized approach accounting for comorbidities, goals of care, and functional outcomes related to speech and swallowing.
口腔癌是一组具有异质性的癌症,根据其发生部位,具有独特的病因学、诊断和治疗考虑因素。尽管吸烟人数的减少导致口腔癌的发病率有所下降,但在某些地区,其发病率仍然很高。病史和体格检查以及组织活检是诊断的关键。虽然手术切除是口腔癌的主要治疗方式,但患者的最佳治疗方案是一种个体化的方法,要考虑到合并症、治疗目标以及与言语和吞咽相关的功能结果。