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肝移植后应激性(章鱼壶样)心肌病经静脉-动脉体外膜肺氧合治疗成功救治

Stress-Induced (Takotsubo) Cardiomyopathy After Liver Transplant Rescued with Venoarterial Extracorporeal Membrane Oxygenation.

作者信息

Caturegli Giorgio, Crane Matthew A, Etchill Eric, Giuliano Kate, Nguyen Michelle, Philosophe Benjamin, Cho Sung-Min, Wittstein Ilan S, Whitman Glenn J R

机构信息

From the Division of Cardiac Surgery.

Division of Transplantation, Department of Surgery.

出版信息

ASAIO J. 2022 Apr 1;68(4):e66-e68. doi: 10.1097/MAT.0000000000001453.

Abstract

Here, we report the case of a 55 year old male patient without significant preexisting cardiovascular disease who received a deceased donor liver transplant. Intraoperatively, the patient developed cardiogenic shock secondary to stress-induced cardiomyopathy or Takotsubo syndrome (TTS), which was refractory to high-dose vasoactive, inotropic medical therapy. The patient was successfully managed with venoarterial extracorporeal membrane oxygenation (VA-ECMO) for 7 days, with complete recovery of cardiac function and maintenance of the hepatic graft. Given the anticipated need for only a short period of support and the expectation of full myocardial recovery, such patients may represent excellent candidates for the use of VA-ECMO.

摘要

在此,我们报告一例55岁男性患者,该患者既往无明显心血管疾病,接受了已故供体肝脏移植。术中,患者因应激性心肌病或Takotsubo综合征(TTS)继发心源性休克,大剂量血管活性、正性肌力药物治疗无效。该患者成功接受静脉-动脉体外膜肺氧合(VA-ECMO)治疗7天,心功能完全恢复,肝移植维持良好。鉴于预计仅需短期支持且期望心肌完全恢复,此类患者可能是使用VA-ECMO的极佳候选者。

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