Roberts J A
Urol Clin North Am. 1986 Nov;13(4):637-45.
The causative agent in nonobstructive pyelonephritis has been shown most often to be P-fimbriated Escherichia coli, mainly because receptors for these fimbriae are found in the bladder, ureter, and the kidney tubules. Age and sex are factors leading to differences in the presentation of the disease, and early diagnosis followed by intensive therapy lessens the chance of renal damage. Renal abscess, perinephric abscess, and pyonephrosis all follow pyelonephritis in the host who is compromised by the presence of stone, obstruction, diabetes, or immunosuppression.
非梗阻性肾盂肾炎的病原体最常见的是P菌毛大肠杆菌,主要是因为在膀胱、输尿管和肾小管中发现了这些菌毛的受体。年龄和性别是导致该病表现存在差异的因素,早期诊断并进行强化治疗可减少肾损伤的几率。肾脓肿、肾周脓肿和肾盂积脓均继发于因结石、梗阻、糖尿病或免疫抑制而身体虚弱的宿主的肾盂肾炎。