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托珠单抗和类固醇治疗新型冠状病毒肺炎炼狱综合征

The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids.

作者信息

Selvaraj Vijairam, Finn Arkadiy, Li Jennifer, Dapaah-Afriyie Kwame

机构信息

Internal Medicine, Miriam Hospital, Providence, USA.

Hospital Medicine, Miriam Hospital, Providence, USA.

出版信息

Cureus. 2022 Feb 25;14(2):e22614. doi: 10.7759/cureus.22614. eCollection 2022 Feb.

Abstract

Hyperinflammation is a key component of severe coronavirus disease 2019 (COVID-19) and is associated with poor outcomes. It is imperative to distinguish severe COVID-19 from hyperinflammatory syndromes such as multisystem inflammatory syndrome (MIS) and hemophagocytic lymphohistiocytosis. There is a subset of post-COVID-19 patients who present with some symptoms characteristic of MIS in adults (MIS-A) yet do not meet all the criteria for a diagnosis. We describe the unique case of a patient with this kind of presentation who clinically improved following tocilizumab and corticosteroid usage.

摘要

高炎症是重症2019冠状病毒病(COVID-19)的关键组成部分,且与不良预后相关。必须将重症COVID-19与多系统炎症综合征(MIS)和噬血细胞性淋巴组织细胞增生症等高炎症综合征区分开来。有一部分COVID-19后患者出现了成人MIS(MIS-A)的一些特征性症状,但未满足所有诊断标准。我们描述了一例具有此类表现的患者的独特病例,该患者在使用托珠单抗和皮质类固醇后临床症状有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d901/8958274/bb7068b94cd0/cureus-0014-00000022614-i01.jpg

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