Blinder Joshua J, Huang Yuan-Shung, Rossano Joseph W, Costarino Andrew T, Li Yimei
Division of Pediatric Cardiology, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, USA.
Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Cardiol Young. 2023 Mar;33(3):420-431. doi: 10.1017/S1047951122001019. Epub 2022 Apr 4.
Children undergoing cardiac surgery have overall improving survival, though they consume substantial resources. Nationwide inpatient cost estimates and costs at longitudinal follow-up are lacking.
Retrospective cohort study of children <19 years of age admitted to Pediatric Health Information System administrative database with an International Classification of Diseases diagnosis code undergoing cardiac surgery. Patients were grouped into neonates (≤30 days of age), infants (31-365 days of age), and children (>1 year) at index procedure. Primary and secondary outcomes included hospital stay and hospital costs at index surgical admission and 1- and 5-year follow-up.
Of the 99,670 cohort patients, neonates comprised 27% and had the highest total hospital costs, though daily hospital costs were lower. Mortality declined (5.6% in 2004 versus 2.5% in 2015, p < 0.0001) while inpatient costs rose (5% increase/year, p < 0.0001). Neonates had greater index diagnosis complexity, greater inpatient costs, required the greatest ICU resources, pharmacotherapy, and respiratory therapy. We found no relationship between hospital surgical volume, mortality, and hospital costs. Neonates had higher cumulative hospital costs at 1- and 5-year follow-up compared to infants and children.
Inpatient hospital costs rose during the study period, driven primarily by longer stay. Neonates had greater complexity index diagnosis, required greater hospital resources, and have higher hospital costs at 1 and 5 years compared to older children. Surgical volume and in-hospital mortality were not associated with costs. Further analyses comprising merged clinical and administrative data are necessary to identify longer stay and cost drivers after paediatric cardiac surgery.
接受心脏手术的儿童总体生存率在不断提高,尽管他们消耗了大量资源。目前缺乏全国范围内的住院费用估计以及长期随访的费用情况。
对年龄小于19岁、因接受心脏手术而被录入儿科健康信息系统管理数据库且具有国际疾病分类诊断代码的儿童进行回顾性队列研究。在首次手术时,将患者分为新生儿(≤30日龄)、婴儿(31 - 365日龄)和儿童(>1岁)。主要和次要结局包括首次手术入院时以及1年和5年随访时的住院时间和住院费用。
在99670名队列患者中,新生儿占27%,其总住院费用最高,尽管每日住院费用较低。死亡率下降(2004年为5.6%,2015年为2.5%,p < 0.0001),而住院费用上升(每年增加5%,p < 0.0001)。新生儿的首次诊断复杂性更高,住院费用更高,需要最多的重症监护资源、药物治疗和呼吸治疗。我们发现医院手术量、死亡率和医院费用之间没有关系。与婴儿和儿童相比,新生儿在1年和5年随访时的累计住院费用更高。
在研究期间,住院费用上升,主要是由于住院时间延长。与大龄儿童相比,新生儿的诊断复杂性指数更高,需要更多的医院资源,且在1年和5年时的住院费用更高。手术量和住院死亡率与费用无关。有必要进行进一步分析,整合临床和管理数据,以确定小儿心脏手术后住院时间延长和费用驱动因素。