Gebel M, Horstkotte H, Köster C, Brunkhorst R, Brandt M, Atay Z
Ultraschall Med. 1986 Oct;7(5):198-202. doi: 10.1055/s-2007-1011948.
2072 patients underwent ultrasonically guided fine-needle biopsy. 1384 patients could be assessed with regard to the final diagnosis. 854 patients underwent fine-needle biopsy of the liver, 322 of the pancreas and 218 of retroperitoneal lesions. The effective sampling rate was 97% for liver biopsies, 86% for pancreas biopsies and 87% for the biopsy of the retroperitoneum. The sensitivity for the detection of malignancies was 90% in liver biopsies, 69% in pancreatic biopsies and 85% in biopsies of the retroperitoneum. The specificity of cytological findings was 100%. Complications occurred in 13 cases. There were two fatalities due to of bleeding, resulting in a complication rate of 0.6% and a lethality of 0.1% of all biopsied patients. The biopsy of the liver proved most dangerous with a complication rate of 1.4%. The bleeding risk of a haemangioma (2.5%) was nearly the same as the bleeding risk of a malignant liver tumour (1.5%).
2072例患者接受了超声引导下细针穿刺活检。1384例患者可根据最终诊断进行评估。854例患者接受了肝脏细针穿刺活检，322例接受了胰腺细针穿刺活检，218例接受了腹膜后病变细针穿刺活检。肝脏活检的有效采样率为97%，胰腺活检为86%，腹膜后活检为87%。肝脏活检检测恶性肿瘤的敏感性为90%，胰腺活检为69%，腹膜后活检为85%。细胞学检查结果的特异性为100%。13例出现并发症。2例因出血死亡，并发症发生率为0.6%，在所有接受活检的患者中致死率为0.1%。肝脏活检被证明是最危险的，并发症发生率为1.4%。血管瘤的出血风险（2.5%）与恶性肝肿瘤的出血风险（1.5%）几乎相同。
