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先天性肌性斜颈婴儿胃食管反流病的患病率:一项前瞻性队列研究。

Prevalence of Gastroesophageal Reflux Disease in Infants With Congenital Muscular Torticollis: A Prospective Cohort Study.

机构信息

Pediatric Physical Therapy (Dr Bess), Johns Hopkins All Children's Hospital, St Petersburg, Florida; School of Physical Therapy (Dr Costa), Gannon University, Ruskin, Florida; Pediatric Physical Therapy (Dr Costa), Children's Therapy Solutions, Bradenton, Florida; Departments of Health Informatics (Mr Nguygen and Dr Amankwah) and Pediatric Gastroenterology (Dr Wilsey), Johns Hopkins All Children's Hospital, St Petersburg, Florida.

出版信息

Pediatr Phys Ther. 2022 Apr 1;34(2):180-183. doi: 10.1097/PEP.0000000000000883.

Abstract

PURPOSE

Clinical experience suggests that gastroesophageal reflux disease (GERD) occurs commonly in infants with congenital muscular torticollis (CMT). However, this is an understudied topic and prospective studies are absent. We determine the prevalence of GERD in infants with CMT, comparing clinical characteristics between CMT infants with and without GERD, and identifying infants with potentially undiagnosed GERD.

METHODS

A prospective cohort study of 155 infants with CMT younger than 12 months with and without GERD was evaluated by pediatric physical therapists.

RESULTS

GERD prevalence was 30.3%, including 6 (3.9%) infants with undiagnosed GERD. Demographic and clinical characteristics were similar in CMT infants with and without GERD.

CONCLUSIONS

This is the first prospective cohort study determining the prevalence of GERD in infants referred for evaluation of CMT. Further prospective studies are needed to determine whether early intervention and treatment of GERD improves outcomes in infants with CMT (see Supplemental Digital Content 1, available at: http://links.lww.com/PPT/A369).

摘要

目的

临床经验表明,先天性肌性斜颈(CMT)婴儿常患有胃食管反流病(GERD)。然而,这是一个研究较少的课题,目前还没有前瞻性研究。我们通过比较有和无 GERD 的 CMT 婴儿的临床特征,确定 CMT 婴儿中 GERD 的患病率,并确定潜在未诊断 GERD 的婴儿。

方法

对 155 名年龄在 12 个月以下且患有和不患有 GERD 的 CMT 婴儿进行前瞻性队列研究,由儿科物理治疗师进行评估。

结果

GERD 的患病率为 30.3%,包括 6 名(3.9%)患有未确诊 GERD 的婴儿。有和无 GERD 的 CMT 婴儿的人口统计学和临床特征相似。

结论

这是第一项针对因 CMT 评估而就诊的婴儿 GERD 患病率的前瞻性队列研究。需要进一步的前瞻性研究来确定 GERD 的早期干预和治疗是否能改善 CMT 婴儿的结局(见补充数字内容 1,可在:http://links.lww.com/PPT/A369 获得)。

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