Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, Pennsylvania.
University of Arkansas for Medical Sciences, Little Rock, Arkansas.
J Arthroplasty. 2022 Sep;37(9):1888-1894. doi: 10.1016/j.arth.2022.03.086. Epub 2022 Apr 6.
Cemented and uncemented femoral stems have shown excellent survivorship and outcomes in primary total hip arthroplasty (THA). Cementless stems have become increasingly common in the United States; however, multiple large database studies have suggested that elderly patients may have fewer complications with a cemented stem. As conclusions from large databases may be limited due to variations in data collection, this study investigated femoral stem survivorship and complication rates based on cement status in non-database studies.
Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were utilized to identify articles for inclusion up until June 2021. Included articles directly compared outcomes and complications between patients undergoing primary THA without femoral stem cementing to those with cementing. Studies were excluded if they utilized large databases or consisted of patients with a preoperative diagnosis of trauma.
Of the 1700 studies, 309 were selected for abstract review and nineteen for full-text review. A total of seven studies were selected. Meta-analyses indicated substantial heterogeneity between studies. There were no differences in revision rates (cementless: 5.53% vs. cemented 8.91%, P = .543), infection rates (cementless: 0.60% vs. cemented: 0.90%, P = .692), or periprosthetic fracture rates (cementless: 0.52% vs. cemented: 0.51%, P = .973) between groups.
There is scarce literature comparing outcomes and complications between cemented and cementless femoral stems in primary elective THA without utilizing a database methodology. In our study, there were no differences in complications detected on meta-analyses. Given previous findings in database studies, additional high-quality cohort studies are required to determine if selected patients may benefit from a cemented femoral stem.
在初次全髋关节置换术(THA)中,骨水泥固定和非骨水泥固定的股骨柄都表现出了优异的存活率和结果。在美国,非骨水泥固定的股骨柄越来越常见;然而,多项大型数据库研究表明,老年患者使用骨水泥固定股骨柄可能并发症更少。由于数据收集的差异,大型数据库的结论可能有限,因此本研究调查了非数据库研究中基于骨水泥状态的股骨柄存活率和并发症发生率。
采用系统评价和荟萃分析的首选报告项目指南,确定截至 2021 年 6 月的纳入研究。纳入的研究直接比较了初次 THA 中未行股骨柄骨水泥固定和行骨水泥固定的患者的结果和并发症。如果研究使用了大型数据库或包含术前诊断为创伤的患者,则将其排除在外。
在 1700 项研究中,有 309 项被选作摘要审查,19 项被选作全文审查。共有 7 项研究被选中。荟萃分析表明研究之间存在很大的异质性。两组患者的翻修率(非骨水泥固定组:5.53% vs. 骨水泥固定组:8.91%,P=0.543)、感染率(非骨水泥固定组:0.60% vs. 骨水泥固定组:0.90%,P=0.692)或假体周围骨折率(非骨水泥固定组:0.52% vs. 骨水泥固定组:0.51%,P=0.973)均无差异。
在不使用数据库方法的情况下,比较初次选择性 THA 中骨水泥固定和非骨水泥固定股骨柄的结果和并发症的文献很少。在我们的研究中,荟萃分析并未发现并发症的差异。鉴于数据库研究中的先前发现,需要更多高质量的队列研究来确定是否有特定患者可能受益于骨水泥固定股骨柄。