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经皮穿刺自体表皮移植术治疗伴有小动脉硬化症的溃疡疼痛控制。

Pain control with punch grafting in ulcers with underlying arteriolosclerosis.

机构信息

Department of Dermatology, La Paz University Hospital, Madrid.

Department of Dermatology, Hospital Universitario Infanta Leonor y Virgen de la Torre, Madrid.

出版信息

J Wound Care. 2022 Apr 2;31(4):356-359. doi: 10.12968/jowc.2022.31.4.356.

Abstract

OBJECTIVE

Martorell hypertensive ischaemic ulcers are often misdiagnosed and can be a clinical and therapeutic challenge. Controversy exists regarding both their underlying triggers and the type of treatment that should be carried out. This study was designed to compare the effectiveness of punch grafting and conventional therapy in pain reduction.

METHOD

A single-centre retrospective study was performed, including 40 patients with a clinical diagnosis of a Martorell ulcer or post-traumatic ulcer secondary to arteriolopathy in the elderly, who were treated with punch grafting (n= 24) or conventional medical treatment (n=16).

RESULTS

There was a statistically and clinically significant reduction in pain after punch grafting. The minimal overall reduction was of three points in visual analogue pain scores. Of the patients who received punch grafting, 80% reported a VAS pain score of 0 at the third follow-up, in contrast with the 44% (n=4) patients who were treated without punch grafting. The mean time to epithelialisation was 82.1 days in patients who received conventional treatment and 43.5 days in those who received punch grafts.

CONCLUSION

Punch grafting is a simple, validated and cost-effective technique that can be performed on an outpatient basis, promotes wound healing and reduces pain. It may control pain and stimulate epithelialisation even if the wound does not present with optimum wound bed characteristics for graft taking. Pain reduction and faster epithelialisation are associated with improvements in patients' quality of life.

摘要

目的

马托雷尔高血压缺血性溃疡经常被误诊,这可能是一个临床和治疗方面的挑战。关于其潜在诱因和应进行的治疗类型,存在争议。本研究旨在比较打孔移植和常规治疗在减轻疼痛方面的效果。

方法

这是一项单中心回顾性研究,共纳入 40 名患有马托雷尔溃疡或老年动脉病变引起的创伤后溃疡的临床诊断患者,他们接受了打孔移植(n=24)或常规药物治疗(n=16)。

结果

打孔移植后疼痛明显减轻,视觉模拟疼痛评分的总降幅至少为 3 分。接受打孔移植的患者中,80%在第三次随访时报告的 VAS 疼痛评分为 0,而未接受打孔移植的患者中这一比例为 44%(n=4)。接受常规治疗的患者上皮化平均时间为 82.1 天,接受打孔移植的患者为 43.5 天。

结论

打孔移植是一种简单、有效且具有成本效益的技术,可以在门诊进行,促进伤口愈合并减轻疼痛。即使伤口不具备最佳的移植物接受床特征,它也可以控制疼痛并刺激上皮化。疼痛减轻和更快的上皮化与患者生活质量的改善相关。

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