Lee Byung Joo, Lee Sang Cheol, Choi Ho Yong, Chang Min Cheol, Park Donghwi
Department of Rehabilitation Medicine, Daegu Fatima Hospital, Daegu 41199, Korea.
Department of Physical Medicine and Rehabilitation, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.
J Clin Med. 2022 Apr 1;11(7):1962. doi: 10.3390/jcm11071962.
Introduction: Frailty syndrome is a complex condition characterized by the gradual deterioration of an individual’s physical, mental, and social functions. Dysphagia is a dysfunction triggered by frailty. However, in patients with frailty syndrome, dysphagia is often undermined, and a proper evaluation is not performed. Therefore, we tried to identify the factors that can provide proper information regarding dysphagia in the frail population. Methods: Patients with dysphagia were divided into those with frailty-induced dysphagia and those with brain-lesion-induced dysphagia. Factors related to the participants’ pulmonary function test (PFT) results were evaluated. The severity of dysphagia was evaluated by determining modified videofluoroscopic dysphagia scale (mVDS) and penetration−aspiration scale (PAS) scores based on videofluoroscopic swallowing studies. Statistical analysis was performed to determine the correlation between PFT results and the parameters indicating dysphagia severity. Results: Multivariate logistic regression analysis revealed that forced vital capacity (FVC) was significantly correlated with mVDS scores in frailty-induced dysphagia (p < 0.05). However, no such significance was detected in brain-lesion-induced dysphagia (p ≥ 0.05). Conclusion: FVC was correlated with the severity of dysphagia (mVDS scores) in patients with frailty-induced dysphagia. Thus, serial FVC-based follow-up can be helpful for understanding patients’ dysphagia status. However, studies with a general population of patients with frailty-induced dysphagia are needed for definite generalization.
衰弱综合征是一种复杂的状况，其特征是个体的身体、心理和社会功能逐渐衰退。吞咽困难是由衰弱引发的一种功能障碍。然而，在衰弱综合征患者中，吞咽困难常常被忽视，未进行适当评估。因此，我们试图确定能够为衰弱人群吞咽困难提供相关信息的因素。方法：将吞咽困难患者分为衰弱所致吞咽困难患者和脑损伤所致吞咽困难患者。评估与参与者肺功能测试（PFT）结果相关的因素。基于视频荧光吞咽造影研究，通过确定改良视频荧光吞咽困难量表（mVDS）和渗透-误吸量表（PAS）评分来评估吞咽困难的严重程度。进行统计分析以确定PFT结果与表明吞咽困难严重程度的参数之间的相关性。结果：多因素逻辑回归分析显示，在衰弱所致吞咽困难中，用力肺活量（FVC）与mVDS评分显著相关（p<0.05）。然而，在脑损伤所致吞咽困难中未检测到这种相关性（p≥0.05）。结论：在衰弱所致吞咽困难患者中，FVC与吞咽困难严重程度（mVDS评分）相关。因此，基于FVC的系列随访有助于了解患者的吞咽困难状况。然而，需要对衰弱所致吞咽困难的普通患者群体进行研究以进行确切的归纳总结。
