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不同算法及截断值在子痫前期早孕期筛查中的效能。

Effectiveness of Different Algorithms and Cut-off Value in Preeclampsia First Trimester Screening.

机构信息

Department of Gynecology and Obstetrics, Pomeranian Medical University, 70-111 Szczecin, Poland.

Department of Obstetrics and Gynecology in Ruda Slaska, Medical University of Silesia, 41-703 Ruda Slaska, Poland.

出版信息

J Pregnancy. 2022 Apr 8;2022:6414857. doi: 10.1155/2022/6414857. eCollection 2022.

Abstract

RESULTS

For the cut-off point >1 : 150, 86 women at an increased risk of eo-PE using algorithm 1 were identified. Of these 86 patients, 83 (96%) were identified using algorithm 2, 62 (72%) using algorithm 3, and 60 (69%) using algorithm 4. In addition, it was demonstrated that between 21% and 29% of women at a low risk of eo-PE could be given acetylsalicylic acid if a screening test was used that did not account for PlGF.

CONCLUSIONS

In order to provide the highest level of health care to pregnant women, it is extremely important that full screening for eo-PE should be ensured. The cheapest algorithm based only on MAP and UtPI resulted in our patients being unnecessarily exposed to complications.

摘要

结果

对于截断值>1:150,使用算法 1 确定了 86 名发生 eo-PE 风险增加的女性。在这 86 名患者中,83 名(96%)使用算法 2 识别,62 名(72%)使用算法 3,60 名(69%)使用算法 4。此外,研究表明,如果使用不考虑 PlGF 的筛查试验,可将 21%至 29%的 eo-PE 低风险女性给予乙酰水杨酸。

结论

为了为孕妇提供最高水平的医疗保健,确保充分筛查 eo-PE 极其重要。基于仅 MAP 和 UtPI 的最便宜算法导致我们的患者不必要地面临并发症。

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本文引用的文献

1
Cut-off values for Gaussian first-trimester screening for early-onset preeclampsia with maternal history, biochemical markers and uterine artery Doppler.
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Screening for pre-eclampsia at 11-13 weeks' gestation: use of pregnancy-associated plasma protein-A, placental growth factor or both.
Ultrasound Obstet Gynecol. 2020 Sep;56(3):400-407. doi: 10.1002/uog.22093. Epub 2020 Aug 5.
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Obstet Gynecol. 2019 Sep;134(3):537-544. doi: 10.1097/AOG.0000000000003413.
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