Calikyan Anoush, Boto Agedi N, Klymenko Valeriia, Siddiqui Imran M
Frank H. Netter School of Medicine at Quinnipiac University, North Haven, CT, USA.
St. Vincent's Medical Center, Department of Pathology, Bridgeport, CT, USA.
Case Rep Gastrointest Med. 2022 Apr 7;2022:1047334. doi: 10.1155/2022/1047334. eCollection 2022.
Carcinosarcoma is a rare malignant neoplasm that is composed of both epithelial and mesenchymal tumor components. Gastric carcinosarcoma is even more rare and is often diagnosed at a late stage. In this report, we investigate a case of early gastric carcinosarcoma with regional lymph node metastasis in a 78-year-old woman. The patient underwent partial gastrectomy, lymphadenectomy, and splenectomy. The tumor was confined to the gastric submucosa, and a biopsy specimen led to a histological diagnosis of carcinosarcoma with adenocarcinoma, squamous-cell carcinoma, and undifferentiated pleomorphic sarcoma components. Metastasis was present in one lymph node and displayed osteosarcomatous differentiation. Vigilant monitoring for recurrence and metastatic disease will be required for this patient.
癌肉瘤是一种罕见的恶性肿瘤,由上皮和间充质肿瘤成分组成。胃癌肉瘤更为罕见,且常于晚期被诊断出来。在本报告中,我们研究了一例78岁女性的早期胃癌肉瘤伴区域淋巴结转移的病例。患者接受了胃部分切除术、淋巴结清扫术和脾切除术。肿瘤局限于胃黏膜下层,活检标本经组织学诊断为具有腺癌、鳞状细胞癌和未分化多形性肉瘤成分的癌肉瘤。一个淋巴结出现转移,并表现出骨肉瘤样分化。该患者需要对复发和转移性疾病进行密切监测。