Gabbard Ryan D, Dryden Stephen C, Reggie Sara N, Fleming James C, Fowler Brian T
Department of Ophthalmology, Prisma Health/University of South Carolina, Columbia, SC, USA.
Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, USA.
Am J Ophthalmol Case Rep. 2022 Apr 3;26:101510. doi: 10.1016/j.ajoc.2022.101510. eCollection 2022 Jun.
To report an unusual case of spontaneous orbital hemorrhage in the setting of DIC and hepatic failure.
A 33-year-old female presented to the Emergency Department (ED) with acute liver failure. During the first week of her hospital admission, she developed unilateral eyelid swelling and proptosis, prompting a consult to ophthalmology. Additional physical examination revealed significantly decreased visual acuity, extraocular muscle restriction, afferent pupillary defect, and increased intraocular pressure. Computed tomography (CT) and ultrasound confirmed the diagnosis of intraorbital hemorrhage. Aggressive management in the form of lateral canthotomy, cantholysis, and septolysis was unable to be performed due to the patient's multiple comorbidities outweighing the potential benefits.
This rare phenomenon is unique from previous existing literature in that the timing of the incident limited the therapeutic options for this patient, additional imaging in the form of ultrasound was utilized in the work-up, and to our knowledge this is the second case of spontaneous orbital hemorrhage as a complication of disseminated intravascular coagulation (DIC) caused by hepatic failure.
报告一例弥散性血管内凝血(DIC)和肝衰竭背景下的罕见自发性眼眶出血病例。
一名33岁女性因急性肝衰竭入住急诊科。在入院的第一周,她出现单侧眼睑肿胀和眼球突出,遂咨询眼科。进一步体格检查发现视力显著下降、眼外肌受限、传入性瞳孔障碍和眼压升高。计算机断层扫描(CT)和超声检查确诊为眶内出血。由于患者多种合并症使潜在益处相形见绌,无法进行外侧眦切开术、眦松解术和隔膜松解术等积极治疗。
这种罕见现象与以往现有文献不同,在于该事件的发生时间限制了该患者的治疗选择,在检查过程中采用了超声这种额外的影像学检查方式,据我们所知,这是肝衰竭导致弥散性血管内凝血(DIC)并发自发性眼眶出血的第二例病例。