Sichuan Provincial Maternity and Child Health Care Hospital (Women's and Children's Hospital Affiliated of Chengdu Medical College), Chengdu.
Chengdu Women's and Children's Central Hospital (School of Medicine, University of Electronic Science and Technology of China), Chengdu.
Ann Med. 2022 Dec;54(1):1112-1117. doi: 10.1080/07853890.2022.2067353.
To summarise the process of conversion of epidural labour analgesia to anaesthesia for caesarean delivery and explore the relationship between duration of labour analgesia and conversion.
Parturients who underwent conversion from epidural labour analgesia to anaesthesia for caesarean delivery between May 2019 and April 2020 at the Chengdu Women's and Children's Central Hospital, Sichuan Maternal and Child Health Hospital, and Jinjiang District Maternal and Child Health Hospital were selected. If the position of the epidural catheter was correct and the effect was good, patients were converted to epidural surgical anaesthesia. If epidural labour analgesia was ineffective, spinal anaesthesia (SA) was administered immediately. For category-1 emergency caesarean sections, general anaesthesia (GA) was administered.
A total of 1084 parturients underwent conversion. Of these, 19 (1.9%) received GA due to the initiation of category-1 emergency caesarean section. 704 (64.9%) were converted to epidural surgical anaesthesia, 2 (0.2%) had failed conversions and were administered GA before delivery, and 357 (32.9%) were converted to SA. Logistic regression analysis showed that prolonged duration of epidural labour analgesia ([Crude odds ratio (OR)=1.065; 95% confidence interval (CI), 1.037-1.094; < .01]; [Adjusted OR = 1.060; 95% CI, 1.031-1.091; < .01]) was an independent risk factor for conversion failure. A receiver operating characteristic curve constructed using duration of epidural labour analgesia showed that parturients with a duration of epidural labour analgesia ≥8 h, more frequently required a change of anaesthesia technique during conversion, and the relative risk of conversion failure was 1.54 (95% CI, 1.23-1.93; < .01).
Prolonged duration of epidural labour analgesia increases the possibility of having an invalid epidural catheter, resulting in an increased risk of conversion failure from epidural labour analgesia to epidural surgical anaesthesia. Further, this risk is higher when the time exceeds 8 h. KEY MESSAGESProlonged duration of epidural labour analgesia > 8 h is associated with conversion failure.If it is impossible to judge whether the conversion is successful immediately, spinal anaesthesia should be administered to minimise complications.
总结硬膜外分娩镇痛转为剖宫产全身麻醉的转化过程,并探讨分娩镇痛持续时间与转化的关系。
选择 2019 年 5 月至 2020 年 4 月在成都市妇女儿童中心医院、四川省妇幼保健院和锦江区妇幼保健院行硬膜外分娩镇痛转化为剖宫产全身麻醉的产妇。若硬膜外导管位置正确,效果良好,则转化为硬膜外手术麻醉;若硬膜外分娩镇痛效果不佳,立即行腰麻(SA)。对于 1 类紧急剖宫产,给予全身麻醉(GA)。
共 1084 例产妇行转化,其中 19 例(1.9%)因 1 类紧急剖宫产而接受 GA。704 例(64.9%)转为硬膜外手术麻醉,2 例(0.2%)转化失败并在分娩前给予 GA,357 例(32.9%)转为 SA。Logistic 回归分析显示,硬膜外分娩镇痛时间延长([粗比值比(OR)=1.065;95%置信区间(CI),1.037-1.094; < .01];[调整 OR=1.060;95% CI,1.031-1.091; < .01])是转化失败的独立危险因素。以硬膜外分娩镇痛时间构建的受试者工作特征曲线显示,硬膜外分娩镇痛时间≥8 h 的产妇,在转化过程中更频繁地需要改变麻醉技术,转化失败的相对风险为 1.54(95% CI,1.23-1.93; < .01)。
硬膜外分娩镇痛时间延长增加了硬膜外导管无效的可能性,导致硬膜外分娩镇痛向硬膜外手术麻醉转化的失败风险增加。此外,当时间超过 8 h 时,这种风险更高。
硬膜外分娩镇痛持续时间>8 h 与转化失败有关。如果不能立即判断转化是否成功,应给予腰麻以减少并发症。