Bao Bei-Xi, Yan Hui, Tang Jia-Guang, Qiu Dao-Jing, Wu Yu-Xuan, Cheng Xiao-Kang
Department of Orthopedic Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, People's Republic of China.
Ther Clin Risk Manag. 2022 Apr 13;18:409-419. doi: 10.2147/TCRM.S352793. eCollection 2022.
To retrospectively analyze the risk factors for adding-on phenomena (AOP) after posterior hemivertebral resection (PHR) and pedicle screw fixation for the treatment of congenital scoliosis (CS) caused by hemivertebral (HV) malformation.
Patients with CS who underwent surgery and were followed up for more than five years were included in this study. The d general data, such as gender, age, HV segment, Risser sign, and triangular cartilage, postoperative complications, and imaging data at different periods, including the standard anteroposterior and lateral x-rays of the total spine were collected.
In total, 58 patients were included in this study, of which 10 experienced AOP and 48 did not. The results of the single-factor analysis showed that there were statistically significant differences between the patients with AOP and those without in terms of the HV direction, lowest instrumented vertebra (LIV)-upper instrumented vertebra (UIV) (P < 0.05), and postoperative trunk shift (P < 0.05). The results of the logistic regression analysis showed that the HV direction and the postoperative trunk displacement distance were the main risk factors for postoperative AOP. The area under the receiver operating characteristic curve was 0.842 (P < 0.001). The best cut-off value of the adding-on index as an indicator of the occurrence of AOP after surgery was 0.67. When the adding-on index was >0.67, the incidence of postoperative AOP was 90.0%, and the non-occurrence rate was 22.9%.
PHR and pedicle screw fixation is an effective way to treat HV malformation in CS. The HV direction, LIV-UIV, and postoperative TS are risk factors for AOP in patients with CS treated with PHR and pedicle screw fixation. The adding-on index has a high degree of accuracy for the prediction of the occurrence of AOP after PHR and pedicle screw fixation.
回顾性分析后路半椎体切除术(PHR)联合椎弓根螺钉内固定治疗半椎体(HV)畸形所致先天性脊柱侧凸(CS)后出现附加现象(AOP)的危险因素。
本研究纳入接受手术且随访超过5年的CS患者。收集患者的一般资料,如性别、年龄、HV节段、Risser征、三角软骨,术后并发症以及不同时期的影像学资料,包括全脊柱标准正侧位X线片。
本研究共纳入58例患者,其中10例出现AOP,48例未出现。单因素分析结果显示,出现AOP的患者与未出现AOP的患者在HV方向、最低固定椎(LIV)-最高固定椎(UIV)(P<0.05)以及术后躯干偏移(P<0.05)方面存在统计学显著差异。Logistic回归分析结果显示,HV方向和术后躯干移位距离是术后AOP的主要危险因素。受试者工作特征曲线下面积为0.842(P<0.001)。作为手术后AOP发生指标的附加指数的最佳截断值为0.67。当附加指数>0.67时,术后AOP发生率为90.0%,未发生率为22.9%。
PHR联合椎弓根螺钉内固定是治疗CS中HV畸形的有效方法。HV方向、LIV-UIV以及术后TS是接受PHR联合椎弓根螺钉内固定治疗的CS患者发生AOP的危险因素。附加指数对预测PHR联合椎弓根螺钉内固定术后AOP的发生具有较高的准确性。