Hirlinger W K, Wick C, Stodtmeister R
Anasth Intensivther Notfallmed. 1986 Dec;21(6):324-6.
20 patients scheduled for cataract extraction were randomly assigned to two groups. Before anaesthesia was induced, group A patients received 0.3 mg/kg body weight diazepam, whereas group B was given 0.15 mg/kg body weight midazolam. The ocular pressure, blood pressure, pulse and respiratory rate were determined and a capillary blood gas analysis was performed prior to the administration of the tranquilizer (time I), after the patient fell asleep (time II) as well as 5 min. after intubation (time III). Before intubation the patients received fentanyl and succinylcholin. The reduction in ocular pressure is initially somewhat less in the midazolam group, but is identical to that in the diazepam group at time III where it fell to 57% of the preinduction value. In combination with fentanyl, these two drugs are suitable for anaesthesia in intraocular surgery.
20名计划进行白内障摘除术的患者被随机分为两组。在诱导麻醉前，A组患者接受0.3mg/kg体重的地西泮，而B组给予0.15mg/kg体重的咪达唑仑。在给予镇静剂前（时间I）、患者入睡后（时间II）以及插管后5分钟（时间III）测定眼压、血压、脉搏和呼吸频率，并进行毛细血管血气分析。插管前患者接受芬太尼和琥珀酰胆碱。咪达唑仑组眼压最初的降低幅度略小于地西泮组，但在时间III时与地西泮组相同，降至诱导前值的57%。与芬太尼联合使用时，这两种药物适用于眼内手术的麻醉。
