Heikkinen E R
Ann Clin Res. 1986;18 Suppl 47:73-83.
Seventy-seven patients underwent 93 stereotactic operations during a five-year period 1980-1984 at the Department of Neurosurgery, Oulu University Central Hospital, Oulu, Finland. Thirty patients were cases of general neurosurgery, consisting of 27 stereotactic biopsies of deep-seated brain tumors with a diagnostic accuracy of 89% (24/27), and three evacuation-aspiration procedures. Two-thirds of the operations (63/93) belonged to the field of functional neurosurgery, the most frequent procedure being stereotactic ventrolateral thalamotomy. In the treatment of drug resistant Parkinsonian tremor and rigidity the success rate was 70% in bilateral and over 90% in unilateral procedures. Operative mortality was 1.1% (1/93 operations) and morbidity 3.2%. Stereotactic technique is mandatory for diagnostic biopsies of deep-seated cerebral lesions. Its combination with computerized tomography ensures better resolution of the lesions and enables more radical therapeutic procedures to be undertaken. Furthermore, stereotactic operations are still indicated in selected cases of medically refractory disorders, especially in epilepsy and involuntary movement disorders.
1980年至1984年期间，芬兰奥卢大学中心医院神经外科对77例患者进行了93次立体定向手术。30例为普通神经外科病例，包括27例深部脑肿瘤的立体定向活检，诊断准确率为89%（24/27），以及3例引流抽吸手术。三分之二的手术（63/93）属于功能神经外科领域，最常见的手术是立体定向腹外侧丘脑切开术。在治疗耐药性帕金森震颤和僵硬方面，双侧手术成功率为70%，单侧手术成功率超过90%。手术死亡率为1.1%（1/93例手术），发病率为3.2%。立体定向技术对于深部脑病变的诊断性活检是必不可少的。它与计算机断层扫描相结合可确保更好地分辨病变，并能够采取更彻底的治疗措施。此外，在某些药物难治性疾病的特定病例中，尤其是癫痫和不自主运动障碍，仍需进行立体定向手术。
