Gilbertson James, Pageau Paul, Ritcey Brandon, Cheng Wei, Burwash-Brennan Talia, Perry Jeffrey J, Woo Michael Y
Department of Emergency Medicine, University of Ottawa, Ottawa, ON, Canada.
Department of Emergency Medicine, University of Ottawa, Ottawa, ON, Canada; Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Ann Emerg Med. 2022 Jun;79(6):529-539. doi: 10.1016/j.annemergmed.2022.02.006. Epub 2022 Apr 21.
Chest ultrasonography has been reported as an accurate imaging modality and potentially superior to chest radiographs in diagnosing traumatic rib fractures. However, few studies have compared ultrasonography to the reference standard of computed tomography (CT), with no systematic reviews published on the topic to date. Our objective was to summarize the evidence comparing the test characteristics of chest ultrasonography to CT in diagnosing rib fractures.
This study was performed and reported in adherence to PRISMA guidelines. We searched 5 databases plus gray literature from inception to October 2021. Two independent reviewers completed study selection, data extraction, and a QUADAS-2 risk of bias assessment. Summary measures were obtained from the Hierarchical Summary Receiver Operating Characteristic model.
From 1,660 citations, we identified 7 studies for inclusion, of which 6 had available 2×2 data for meta-analysis (n = 663). Of the 6 studies, 3 involved emergency department-performed ultrasonography and 3 radiology-performed ultrasonography. Chest ultrasonography had a pooled sensitivity of 89.3% (95% confidence interval [CI], 81.1 to 94.3) and specificity of 98.4% (95% CI, 90.2 to 99.8) compared with CT imaging for the diagnosis of any rib fracture. The finding of a fracture on ultrasonography, defined as an underlying cortical irregularity, was associated with a +likelihood ratio (LR) of 55.7 (95% CI, 8.5 to 363.4) for CT diagnosed rib fracture, while the absence of ultrasonography fracture held a -LR of 0.11 (95% CI, 0.06 to 0.20). We were unable to detect a difference in test characteristics between emergency department- and radiology-performed ultrasonography (P=.11). The overall risk of bias of included studies was high, with patient selection identified as the highest risk domain.
Chest ultrasonography is both sensitive and highly specific in diagnosing rib fractures following blunt trauma.
据报道,胸部超声检查是一种准确的成像方式,在诊断创伤性肋骨骨折方面可能优于胸部X光片。然而,很少有研究将超声检查与计算机断层扫描(CT)这一参考标准进行比较,迄今为止,尚未发表关于该主题的系统评价。我们的目的是总结将胸部超声检查与CT在诊断肋骨骨折方面的检查特征进行比较的证据。
本研究按照PRISMA指南进行并报告。我们检索了5个数据库以及自开始至2021年10月的灰色文献。两名独立评审员完成了研究筛选、数据提取以及QUADAS - 2偏倚风险评估。汇总测量值从分层汇总接受者操作特征模型中获得。
从1660条引用文献中,我们确定了7项纳入研究,其中6项有可用于荟萃分析的2×2数据(n = 663)。在这6项研究中,3项涉及急诊科进行的超声检查,3项涉及放射科进行的超声检查。与CT成像相比,胸部超声检查对任何肋骨骨折诊断的汇总敏感性为89.3%(95%置信区间[CI],81.1至94.3),特异性为98.4%(95%CI,90.2至99.8)。超声检查发现骨折(定义为潜在的皮质不规则)与CT诊断肋骨骨折的阳性似然比(LR)为55.7(95%CI,8.5至363.4),而超声检查未发现骨折的阴性似然比为0.11(95%CI,0.06至0.20)。我们未能检测到急诊科和放射科进行的超声检查在检查特征上的差异(P = 0.11)。纳入研究的总体偏倚风险较高,患者选择被确定为最高风险领域。
胸部超声检查在诊断钝性创伤后的肋骨骨折方面既敏感又具有高度特异性。