Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA.
Division of Nutrition, Mayo Clinic, Jacksonville, FL, USA.
Inflamm Bowel Dis. 2022 Oct 3;28(10):1592-1602. doi: 10.1093/ibd/izac085.
Malnutrition is a very common and often underrecognized condition among patients with inflammatory bowel diseases (IBD). This is most commonly due to increased nutritional requirements and gastrointestinal losses, along with reduced oral intake. Screening for malnutrition is an essential component of managing both inpatients and outpatients with IBD. Although enteral nutrition is the preferred route of supplementation, parenteral nutrition (PN) remains an important strategy and should be considered in certain situations, such as cases with short-bowel syndrome, high-output intestinal fistula, prolonged ileus, or small-bowel obstruction. Appropriate use of PN is critical in order to prevent associated complications. This review addresses the common indications for use of PN, the composition of PN, and the possible complications encountered with PN use, as well as scenarios of inappropriate PN use among patients with IBD. A clinical management algorithm for utilizing PN among patients with IBD is proposed in this review.
营养不良是炎症性肠病(IBD)患者中非常常见且常常未被识别的一种情况。这主要是由于营养需求增加和胃肠道丢失,以及口服摄入减少所致。对营养不良进行筛查是管理 IBD 住院和门诊患者的重要组成部分。虽然肠内营养是首选的补充途径,但肠外营养(PN)仍然是一种重要的策略,在某些情况下应考虑使用,例如短肠综合征、高输出肠道瘘、长时间肠梗阻或小肠梗阻的情况。为了预防相关并发症,PN 的合理使用至关重要。本文综述了 PN 使用的常见适应证、PN 的组成以及使用 PN 时可能遇到的并发症,以及 IBD 患者不恰当使用 PN 的情况。本文还提出了一种在 IBD 患者中使用 PN 的临床管理算法。