Cho Hyungwoo
Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Blood Res. 2022 Apr 30;57(S1):20-26. doi: 10.5045/br.2022.2022035.
The term "monoclonal gammopathy of clinical significance" (MGCS) refers to any plasma cell or B-cell clonal disorder that does not meet the current criteria for malignant disorders but produces a monoclonal protein that directly or indirectly results in organ damage. The most commonly affected organs are the kidneys, nerves, and skin. This review summarizes the current classification of MGCS and its diagnostic and treatment approaches.
“具有临床意义的单克隆丙种球蛋白病”(MGCS)这一术语是指任何不符合当前恶性疾病标准,但产生直接或间接导致器官损害的单克隆蛋白的浆细胞或B细胞克隆性疾病。最常受影响的器官是肾脏、神经和皮肤。本综述总结了MGCS的当前分类及其诊断和治疗方法。