术前中性粒细胞与淋巴细胞比值在预测 3 型开放性胫骨骨干骨折感染中的价值
Does the pre-operative neutrophil-lymphocyte ratio have a predictive value in detecting infection in type 3 open tibia diaphysis fractures?
机构信息
Department of Orthopaedics and Traumatology, Necmettin Erbakan University Meram Faculty of Medicine, Konya-Turkey.
出版信息
Ulus Travma Acil Cerrahi Derg. 2022 May;28(5):693-697. doi: 10.14744/tjtes.2021.31766.
BACKGROUND
This retrospective study was aimed to investigate whether the pre-operative neutrophil-lymphocyte (N/L) ratio has a predictive value in terms of evaluating the development of infection in patients with type 3 open fractures of the tibia diaphysis.
METHODS
A total of 72 patients with type 3 open tibia fractures who consulted to the emergency service at the Necmettin Er-bakan University Meram Faculty of Medicine, during the period between 2015 and 2020 were retrospectively examined. A total of 39 patients who underwent external fixator in the first treatment were included in the study. The information pertaining to the patients such as the patient demographic data, type of injury, wound cultures, and N/L rates during the pre-operative period were recorded. Patients were divided into two groups based on the presence of infection: Group 1 (12 patients) consisted of patients who had infec-tion, and Group 2 (27 patients) consisted of patients who had no infection.
RESULTS
34 (87.2%) of the patients were male and 5 (12.8%) were women. The mean age of these patients was 43.18±18.67 (19-80). Infection was detected in 12 (30.8%) out of 39 patients. Of these patients, 9 (75%) were monomicrobial, and 3 (25%) were polymicrobial. The most common mechanism of the injury was gunshot injury in 16 (41%) of all patients. However, there was no sig-nificant difference between the groups in terms of mechanism of injury (p=0.445). When all patients were examined in terms of N/L rates and presence of infection, there was no significant difference between Group 1 and Group 2 (p=0.976).
CONCLUSION
Although N/L ratio of the blood in the pre-operative period has a predictive value for chronic diseases, we believe that it has no predictive value for detecting infection in patients with type 3 acute open tibia fractures.
背景
本回顾性研究旨在探讨术前中性粒细胞与淋巴细胞（N/L）比值是否对胫骨骨干 3 型开放性骨折患者感染的发生具有预测价值。
方法
回顾性分析 2015 年至 2020 年期间在 Necmettin Erbakan 大学 Meram 医学院急诊就诊的 72 例胫骨 3 型开放性骨折患者。共纳入 39 例初次治疗采用外固定架的患者。记录患者的人口统计学资料、损伤类型、伤口培养物和术前 N/L 比值等信息。根据是否存在感染将患者分为两组：感染组（12 例）和无感染组（27 例）。
结果
39 例患者中，男性 34 例（87.2%），女性 5 例（12.8%）；平均年龄 43.18±18.67 岁（19-80 岁）。39 例患者中，感染 12 例（30.8%）。其中，9 例（75%）为单一致病菌感染，3 例（25%）为多致病菌感染。所有患者中，枪伤 16 例（41%）为最常见的致伤机制。但两组在致伤机制方面无显著差异（p=0.445）。所有患者的 N/L 比值与感染情况进行比较时，感染组与无感染组之间无显著差异（p=0.976）。
结论
虽然术前血液 N/L 比值对慢性疾病具有预测价值，但我们认为其对 3 型急性开放性胫骨骨折患者感染的检测无预测价值。
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