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抗精神病药恶性综合征(NMS)病例报告:如何进行早期诊断

A Case Report on Neuroleptic Malignant Syndrome (NMS): How to Approach an Early Diagnosis.

作者信息

Paul Tanya, Karam Alvina, Paul Trissa, Loh Hanyou, Ferrer Gerardo F

机构信息

Psychiatry, Larkin Community Hospital, South Miami, USA.

Medicine, Avalon University School of Medicine, Curacao, CUW.

出版信息

Cureus. 2022 Mar 31;14(3):e23695. doi: 10.7759/cureus.23695. eCollection 2022 Mar.

Abstract

Neuroleptic malignant syndrome (NMS) is a life-threatening neurological emergency that has been observed to occur in some patients following the administration of anti-dopaminergic agents or the rapid withdrawal of dopaminergic medications. In this report, the authors present a case of a 51-year-old male patient with a known history of cocaine abuse, who was given quetiapine during his hospitalization. This precipitated an episode of NMS that eventually concluded uneventfully due to quick diagnosis and management. Prompt recognition of the condition is required to reduce significant morbidity and mortality. Ultimately, maintaining vigilance for the clinical features of NMS is crucial for timely diagnosis and intervention.

摘要

抗精神病药恶性综合征(NMS)是一种危及生命的神经急症,在一些患者使用抗多巴胺能药物后或迅速停用多巴胺能药物后被观察到会发生。在本报告中,作者介绍了一名有可卡因滥用史的51岁男性患者的病例,该患者在住院期间服用了喹硫平。这引发了一次抗精神病药恶性综合征发作,由于诊断和处理迅速,最终病情平稳结束。需要迅速识别该病症以降低严重的发病率和死亡率。最终,对抗精神病药恶性综合征的临床特征保持警惕对于及时诊断和干预至关重要。

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