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[中毒性巨结肠:慢性便秘的一种罕见并发症。三例儿科病例]

[Toxic Megacolon: A rare complication of chronic constipation. Three Pediatric Cases].

作者信息

Muñoz P Macarena, Andueza A Fernanda, Santos M Marcela

机构信息

Hospital Exequiel González Cortés, Universidad de Chile, Santiago, Chile.

出版信息

Andes Pediatr. 2022 Feb;93(1):105-109. doi: 10.32641/andespediatr.v93i1.3479. Epub 2021 Sep 8.

Abstract

INTRODUCTION

Chronic constipation is a frequent pathology in the pediatric age that affects the quality of life of pa tients and their families. Its management is usually complex and long associated with poor adheren ce. Toxic megacolon is a serious, potentially lethal disease when chronic constipation is left untreated or poor adherence to treatment.

OBJECTIVE

To report 3 pediatric cases of toxic megacolon as a com plication of poorly managed chronic constipation.

CLINICAL CASES

Three males patients, aged 6 to 13 years, with a history of chronic constipation and poor adherence to treatment are discussed. They were admitted to the emergency department with clinical findings of toxic megacolon (intestinal dilation and signs of systemic toxicity). Given their condition, all patients required management in the critical patient unit (CPU) and early surgical intervention, undergoing ostomy. All presented fa vorable outcome, performing stoma reversal surgery between 8-24 months later. In all cases, organic cause of the constipation was ruled out.

CONCLUSIONS

Toxic megacolon is an infrequent but highly morbid and potentially lethal disease. It requires a high index of suspicion as well as multidisciplinary medical-surgical management.

摘要

引言

慢性便秘是儿科常见病症,会影响患者及其家庭的生活质量。其治疗通常较为复杂且长期,与依从性差相关。当慢性便秘未得到治疗或治疗依从性差时,中毒性巨结肠是一种严重的、可能致命的疾病。

目的

报告3例因慢性便秘管理不善而并发中毒性巨结肠的儿科病例。

临床病例

讨论了3例年龄在6至13岁之间、有慢性便秘病史且治疗依从性差的男性患者。他们因中毒性巨结肠的临床表现(肠扩张和全身毒性体征)被收入急诊科。鉴于他们的病情,所有患者都需要在重症监护病房(CPU)进行治疗并尽早进行手术干预,接受造口术。所有患者均取得良好预后,在8至24个月后进行了造口还纳手术。所有病例均排除了便秘的器质性原因。

结论

中毒性巨结肠是一种罕见但高发病率且可能致命的疾病。它需要高度的怀疑指数以及多学科的医疗手术管理。

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