Department of Nuclear Medicine, Public Assistance Hospitals of Marseille, Timone University Hospital, Marseille, France; Centre Européen de Recherche en Imagerie Médicale, Aix-Marseille University, Marseille, France.
Department of Neurology and Movement Disorders, AP-HM, Timone University Hospital, Marseille, France; CRMBM, CEMEREM, CNRS, Aix Marseille Univ, Marseille, France.
Rev Neurol (Paris). 2022 May;178(5):484-489. doi: 10.1016/j.neurol.2022.03.002. Epub 2022 May 5.
Nuclear medicine with positron emission tomography (PET) and single photon emission computed tomography (SPECT) develops powerful tools in molecular imaging to help clinicians in the challenging diagnosis of parkinsonism. These techniques can provide biomarkers for neurodegenerative parkinsonism and to distinguish Parkinson disease (PD) from atypical parkinsonism. This review summarizes the main SPECT and PET contributions to the diagnosis of parkinsonism. We will also discuss new technologies in the field of nuclear imaging and their potential contribution to the diagnosis of parkinsonian syndromes.
核医学中的正电子发射断层扫描（PET）和单光子发射计算机断层扫描（SPECT）为分子成像提供了强大的工具，有助于临床医生对帕金森病进行具有挑战性的诊断。这些技术可以为神经退行性帕金森病提供生物标志物，并将帕金森病（PD）与非典型帕金森病区分开来。本文综述了 SPECT 和 PET 在帕金森病诊断中的主要贡献。我们还将讨论核成像领域的新技术及其对帕金森综合征诊断的潜在贡献。
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