Ciancio Gaetano, Tabbara Marina M, Farag Ahmed, Salerno Tomas
Department of Surgery, University of Miami Miller School of Medicine, Jackson Memorial Hospital Miami, FL, USA.
Miami Transplant Institute, University of Miami Miller School of Medicine, Jackson Memorial Hospital Miami, FL, USA.
Am J Clin Exp Urol. 2022 Apr 15;10(2):123-128. eCollection 2022.
Renal cell carcinoma (RCC) with inferior vena cava (IVC) and right atrium (RA) tumor thrombus (TT) is a rare occurrence and its resection is surgical challenge. Management becomes even more difficult when the TT causes hepatic vein obstruction and leads to Budd-Chiari syndrome. We report a case of 68-year-old male with right RCC with IVC and RA TT with associated Budd-Chiari syndrome. Surgical management was performed without cardiopulmonary bypass (CPB) and re-sternotomy due to the patient's previous history of coronary artery bypass grafting (CABG) for 3 vessel coronary artery disease. Through a transabdominal approach, the diaphragm was dissected off the IVC and the RA was gently pulled into the abdomen and clamped under transesophageal echocardiogram (TEE) control. As use of CPB in these surgeries is associated with increased morbidity and mortality, this organ transplant-based approach is encouraged for patients requiring resection of RCC with supradiaphragmatic TT.
伴有下腔静脉(IVC)及右心房(RA)肿瘤血栓(TT)的肾细胞癌(RCC)较为罕见,其切除手术具有挑战性。当肿瘤血栓导致肝静脉梗阻并引发布加综合征时,治疗会变得更加困难。我们报告一例68岁男性患者,患有右侧肾细胞癌并伴有下腔静脉及右心房肿瘤血栓,同时合并布加综合征。由于该患者既往有因三支冠状动脉病变行冠状动脉搭桥术(CABG)的病史,故在无体外循环(CPB)及再次开胸的情况下进行了手术治疗。通过经腹入路,将膈肌从下腔静脉分离,在经食管超声心动图(TEE)监测下,轻柔地将右心房拉入腹腔并钳夹。鉴于在这类手术中使用体外循环会增加发病率和死亡率,对于需要切除伴有膈上肿瘤血栓的肾细胞癌患者,鼓励采用这种基于器官移植的方法。