Zhang Ying-An, Wang Wei, Li Xiao-Li, Pan Jie, Li Zhao-Ai
Department of Gynecology and Obstetrics, Children's Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, China.
Department of Laboratory Medicine, Shanxi Provincial People's Hospital, Taiyuan, China.
Open Med (Wars). 2022 Apr 22;17(1):801-807. doi: 10.1515/med-2022-0467. eCollection 2022.
The objective of this study was to compare the clinical effectiveness of traditional vaginal surgery and transvaginal mesh (TVM) surgery on severe pelvic organ prolapse (POP). We performed a retrospective chart review study of 258 severe POP patients who underwent surgery between November 2010 and September 2016. One hundred forty patients underwent traditional vaginal surgery and 118 TVM surgery. The Pelvic Organ Prolapse Quantitation (POP-Q) staging was used for objective evaluation. The Pelvic Floor Distress Inventory-20 (PFDI-20), Pelvic Floor Disease Life Impact Questionnaire Simplified Version-7 (PFIQ-7), and Pelvic Organ Prolapse/Incontinence Sexual Function Questionnaire (PISQ-12) were used for subjective evaluation. Their complications were also recorded. All the data were collected in the outpatient department through the follow-up at 3 months, 1, 3, and 5 years after the operation. Forty patients in the traditional vaginal surgery group and 25 in the TVM group were lost to follow-up. There was no difference in the POP-Q score between the groups ( = 0.346). The recurrence rate increased with follow-up time, reaching nearly 20% in the two groups by 5 years. The TVM group has higher PFDI-20 and PFIQ-7 scores and lower PISQ-12 scores than the traditional vaginal surgery group at six months, 1, 3, and 5 years, respectively ( < 0.001). Mesh exposure has occurred in the TVM group. Both surgeries showed similar objective satisfaction and recurrence rate. However, traditional vaginal surgery has higher subjective satisfaction than TVM in our study and does not risk exposure to prosthetic material.
本研究的目的是比较传统阴道手术和经阴道网片(TVM)手术治疗重度盆腔器官脱垂(POP)的临床效果。我们对2010年11月至2016年9月期间接受手术的258例重度POP患者进行了回顾性病历审查研究。140例患者接受了传统阴道手术,118例接受了TVM手术。采用盆腔器官脱垂定量(POP-Q)分期进行客观评估。使用盆底困扰量表-20(PFDI-20)、盆底疾病生活影响问卷简化版-7(PFIQ-7)和盆腔器官脱垂/尿失禁性功能问卷(PISQ-12)进行主观评估。同时记录它们的并发症。所有数据均在门诊通过术后3个月、1年、3年和5年的随访收集。传统阴道手术组有40例患者失访,TVM组有25例患者失访。两组之间的POP-Q评分无差异(P = 0.346)。复发率随随访时间增加,到5年时两组复发率接近20%。在术后6个月、1年、3年和5年时,TVM组的PFDI-20和PFIQ-7评分分别高于传统阴道手术组,而PISQ-12评分低于传统阴道手术组(P < 0.001)。TVM组出现了网片暴露。两种手术的客观满意度和复发率相似。然而,在我们的研究中,传统阴道手术的主观满意度高于TVM手术,且不存在假体材料暴露的风险。