Bulman Page Philip C, Goodyear Ross L, Chan Yohan, Slawin Alexandra M Z, Allin Steven M
School of Chemistry, University of East Anglia, Norwich Research Park Norwich Norfolk NR4 7TJ UK
School of Chemistry, University of St Andrews St Andrews Scotland KY16 9ST UK.
RSC Adv. 2019 Sep 24;9(51):30019-30032. doi: 10.1039/c9ra07244f. eCollection 2019 Sep 18.
A formal, stereocontrolled synthesis of lactacystin has been completed from -Bul-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.
已从β-丝氨酸完成了乳胞素的正式、立体控制合成,得到关键中间体13,其也可用于一系列C-9类似物的合成。