Health Science Univercity Ankara Researching and Training Hospital, Departmant of Ophthalmolgy, Ankara, Turkey.
Int Ophthalmol. 2022 Nov;42(11):3567-3577. doi: 10.1007/s10792-022-02357-8. Epub 2022 May 10.
The aim of this study was to investigate the prevalence of congenital optic disc anomalies in Turkey.
The 11,123 eyes of 5570 patients were screened for optic disc anomalies. All patients were underwent a complete ophthalmic examination including best corrected visual acuity, refraction, spherical equivalent, slit lamp biomicroscopy, intraocular pressure measurements, dilated stereoscopic fundus examination. Data analyses were performed by using SPSS for Windows, version 22.0 (SPSS Inc., Chicago, IL, United States).
11,123 eyes of 5570 participants were screened. Of the 5570 participants who underwent optic disc examination, 246 eyes of 174 patients (3.12%, 95% CIs 2.66-3.58%) had optic disc anormalies. 92 (52.9%) were female, 82 (47.1%) were male and the mean of age was 44.25 ± 15.67 years. 72 (41.4%) patients were bilateral, 102 (58.6%) patients were unilateral involvement. The tilted disc was the most common anomaly and was found at least one eye in 46 patients (75 eyes) and 0.83% of all screened patients. Peripapillary myelinated nerve fibers was the second common anomaly and was found at least one eye in 31 subjects (35 eyes) and 0.56% of all screened subjects. Peripapillary atrophy was the third common anomaly, and was found in at least one eye in 24 patients (37 eyes) and 0.43% of all screened subjects.
To our knowledge, this is the first study that the prevalences of all congenital optic disc anomalies from Turkey. The prevalence of congenital optic disc anomalies is higher than in other countries.
本研究旨在调查土耳其先天性视盘异常的患病率。
对 5570 例患者的 11123 只眼进行视盘异常筛查。所有患者均行全面眼科检查,包括最佳矫正视力、屈光度、球镜等效值、裂隙灯显微镜检查、眼压测量、散瞳立体眼底检查。数据分析采用 SPSS for Windows 版本 22.0(SPSS Inc.,芝加哥,IL,美国)。
对 5570 名接受视盘检查的参与者进行了 11123 只眼的筛查。在接受视盘检查的 5570 名参与者中,有 174 名患者的 246 只眼(3.12%,95%置信区间 2.66-3.58%)存在视盘异常。92 例(52.9%)为女性,82 例(47.1%)为男性,平均年龄为 44.25±15.67 岁。72 例(41.4%)为双侧,102 例(58.6%)为单侧。倾斜盘是最常见的异常,在 46 名患者(75 只眼)和所有筛查患者的 0.83%中至少有一只眼存在。视盘周围髓鞘神经纤维是第二常见的异常,在 31 名患者(35 只眼)和所有筛查患者的 0.56%中至少有一只眼存在。视盘周围萎缩是第三常见的异常,在 24 名患者(37 只眼)和所有筛查患者的 0.43%中至少有一只眼存在。
据我们所知,这是第一项来自土耳其的所有先天性视盘异常患病率的研究。先天性视盘异常的患病率高于其他国家。