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珊瑚的生物信息学:从珊瑚整体共生体中研究异质组学数据,以深入了解珊瑚礁的健康和恢复力。

Bioinformatics of Corals: Investigating Heterogeneous Omics Data from Coral Holobionts for Insight into Reef Health and Resilience.

机构信息

Department of Computer Science, Tufts University, Medford, Massachusetts, USA; email:

Department of Biological Sciences, University of Rhode Island, Kingston, Rhode Island, USA; email:

出版信息

Annu Rev Biomed Data Sci. 2022 Aug 10;5:205-231. doi: 10.1146/annurev-biodatasci-122120-030732. Epub 2022 May 10.

Abstract

Coral reefs are home to over two million species and provide habitat for roughly 25% of all marine animals, but they are being severely threatened by pollution and climate change. A large amount of genomic, transcriptomic, and other omics data is becoming increasingly available from different species of reef-building corals, the unicellular dinoflagellates, and the coral microbiome (bacteria, archaea, viruses, fungi, etc.). Such new data present an opportunity for bioinformatics researchers and computational biologists to contribute to a timely, compelling, and urgent investigation of critical factors that influence reef health and resilience.

摘要

珊瑚礁是两百多万种物种的家园,为大约 25%的海洋动物提供栖息地,但它们正受到污染和气候变化的严重威胁。越来越多的基因组、转录组和其他组学数据可从不同种类的造礁珊瑚、单细胞甲藻和珊瑚微生物组(细菌、古菌、病毒、真菌等)中获得。这些新数据为生物信息学研究人员和计算生物学家提供了一个机会,有助于及时、有力和紧迫地调查影响珊瑚礁健康和恢复力的关键因素。

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