Department of Surgery, Danbury Hospital, Nuvance Health System, Danbury, CT, USA.
Division of Thoracic Surgery, Department of Surgery, Memorial Healthcare System, South Broward, FL, USA.
Eur J Cardiothorac Surg. 2022 Aug 3;62(3). doi: 10.1093/ejcts/ezac281.
Locally advanced lung cancers present a significant challenge to minimally invasive thoracic surgeons. An increasing number of centres have adopted robotic-assisted thoracoscopic surgeries for these complex operations. In this study, we compare surgical margins achieved, conversion rates to thoracotomy, perioperative mortality and 30-day readmission rates for robotic and video-assisted thoracoscopic surgery (VATS) lobectomy for locally advanced lung cancers.
Using the National Cancer Database, we identified patients with non-small-cell lung cancer who received neoadjuvant chemotherapy/radiotherapy, had clinical N1/N2 disease or in the absence of these 2 features had a tumour >5 cm treated with either robotic or VATS lobectomy between 2010 and 2016. Perioperative outcomes and conversion rates were compared between robotic and VATS lobectomy.
A total of 9512 patients met our inclusion criteria with 2123 (22.3%) treated with robotic lobectomy and 7389 (77.7%) treated with VATS lobectomy. Comparable R0 resections, 30- and 90-day mortality and 30-day readmission rates were observed for robotic and VATS lobectomy while a higher rate of conversion to thoracotomy was observed for VATS (aOR = 1.99, 95% confidence interval = 1.65, 2.39, P < 0.001).
Our analysis of the National Cancer Database suggests that robotic lobectomy for complex lung resections achieves similar perioperative outcomes and R0 resections as VATS lobectomy with the exception of a lower rate of conversion to thoracotomy.
局部晚期肺癌对微创胸外科医生来说是一个重大挑战。越来越多的中心已采用机器人辅助胸腔镜手术来进行这些复杂的手术。在这项研究中,我们比较了机器人辅助和电视辅助胸腔镜手术(VATS)肺叶切除术治疗局部晚期肺癌的手术切缘、中转开胸率、围手术期死亡率和 30 天再入院率。
我们使用国家癌症数据库,确定了 2010 年至 2016 年间接受新辅助化疗/放疗、临床 N1/N2 期疾病或在缺乏这两种特征的情况下,肿瘤>5cm 的非小细胞肺癌患者,这些患者接受了机器人或 VATS 肺叶切除术治疗。比较了机器人和 VATS 肺叶切除术的围手术期结果和中转率。
共有 9512 名患者符合我们的纳入标准,其中 2123 名(22.3%)接受了机器人肺叶切除术,7389 名(77.7%)接受了 VATS 肺叶切除术。机器人和 VATS 肺叶切除术的 R0 切除率、30 天和 90 天死亡率以及 30 天再入院率相似,但 VATS 中转开胸率较高(aOR=1.99,95%置信区间=1.65,2.39,P<0.001)。
我们对国家癌症数据库的分析表明,机器人肺叶切除术治疗复杂的肺切除术与 VATS 肺叶切除术具有相似的围手术期结果和 R0 切除率,除了中转开胸率较低。