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比较医院和关键人群主导的卫生服务提供者对暴露前预防 (PrEP) 的态度和知识:对泰国全民健康覆盖实施的教训。

A comparison of attitudes and knowledge of pre-exposure prophylaxis (PrEP) between hospital and Key Population Led Health Service providers: Lessons for Thailand's Universal Health Coverage implementation.

机构信息

Faculty of Public Health, Chiang Mai University, Chiang Mai, Thailand.

School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Selangor, Malaysia.

出版信息

PLoS One. 2022 May 12;17(5):e0268407. doi: 10.1371/journal.pone.0268407. eCollection 2022.

Abstract

BACKGROUND

HIV Pre-exposure prophylaxis (PrEP) has demonstrated efficacy and effectiveness among high-risk populations. In Thailand, PrEP has been included in the National Guidelines on HIV/AIDS Treatment and Prevention since 2014. As a part of the national monitoring and evaluation framework for Thailand's universal coverage inclusion, this cross-sectional survey was conducted to assess knowledge of, attitudes to and practice (KAP) of PrEP service providers in Thailand.

METHODS

We conducted a cross-sectional survey to explore knowledge of, and attitudes towards PrEP among providers from hospital and Key Population Led Health Services (KPLHS) settings. The questionnaire was distributed online in July 2020. Descriptive and univariate analysis using an independent-sample t-test were applied in the analyses. Attitudes were ranked from the most negative (score of 1) to the most positive (score of 5).

RESULTS

Overall, there were 196 respondents (158 from hospitals and 38 from KPLHS) in which most hospital providers are female nurse practitioners while half of those from KPLHS report current gender as gay. Most respondents report a high level of PrEP knowledge and support provision in all high-risk groups with residual concern regarding anti-retroviral drugs resistance. Over two-fifths of providers from both settings perceive that PrEP would result in risk compensation and half of KPLHS providers are concerned regarding risk of sexual transmitted infections. Limited PrEP counselling time is a challenge for hospital providers.

CONCLUSIONS

Service integration between both settings, more involvement and distribution of KPLHS in reaching key populations would be essential in optimizing PrEP uptake and retention. Continuing support particularly in raising awareness about PrEP among healthcare providers and key populations, facilities and manpower, unlimited quota of patient recruitment and PrEP training to strengthen providers' confidence and knowledge would be essential for successful PrEP implementation.

摘要

背景

艾滋病毒暴露前预防(PrEP)在高危人群中已被证明具有疗效和效果。自 2014 年以来,泰国已将 PrEP 纳入国家艾滋病毒/艾滋病治疗和预防指南。作为泰国全民覆盖纳入国家监测和评估框架的一部分,本横断面调查旨在评估泰国 PrEP 服务提供者的知识、态度和实践(KAP)。

方法

我们进行了一项横断面调查,以探讨医院和重点人群主导的卫生服务(KPLHS)机构提供者对 PrEP 的了解程度、态度和做法。调查问卷于 2020 年 7 月在网上分发。在分析中使用独立样本 t 检验进行描述性和单变量分析。态度从最负面(得分为 1)到最正面(得分为 5)进行排名。

结果

总体而言,共有 196 名受访者(158 名来自医院,38 名来自 KPLHS),其中大多数医院提供者是女性执业护士,而一半来自 KPLHS 的人报告目前的性别为男同性恋。大多数受访者报告在所有高危人群中具有高水平的 PrEP 知识和支持提供,但对抗逆转录病毒药物耐药性仍存在担忧。来自这两个机构的超过五分之二的提供者认为 PrEP 会导致风险补偿,一半的 KPLHS 提供者担心性传播感染的风险。医院提供者面临有限的 PrEP 咨询时间的挑战。

结论

两个机构之间的服务整合,更多地让 KPLHS 参与并接触到关键人群,对于优化 PrEP 的接受和保留至关重要。继续支持,特别是提高医疗保健提供者和关键人群对 PrEP 的认识,提供设施和人力,无限额招募患者和 PrEP 培训,以增强提供者的信心和知识,对于成功实施 PrEP 至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b03/9098026/fa9ef9efd366/pone.0268407.g001.jpg

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