Department of Trauma and Orthopedic Surgery, Cologne-Merheim Medical Centre (CMMC), University of Witten/Herdecke, Ostmerheimerstr.200, 51109, Cologne, Germany.
Institute for Research in Operative Medicine (IFOM), University of Witten/Herdecke, Cologne, Germany.
Eur J Trauma Emerg Surg. 2022 Dec;48(6):4623-4630. doi: 10.1007/s00068-022-01988-x. Epub 2022 May 12.
The indication for pre-hospital endotracheal intubation (ETI) must be well considered as it is associated with several risks and complications. The current guidelines recommend, among other things, ETI in case of shock (systolic blood pressure < 90 mmHg). This study aims to investigate whether isolated hypotension without loss of consciousness is a useful criterion for ETI.
The data of 37,369 patients taken from the TraumaRegister DGU® were evaluated in a retrospective study with regard to pre-hospital ETI and the underlying indications. Inclusion criteria were the presence of any relevant injuries (Abbreviated Injury Scale [AIS] ≥ 3) and complete pre-hospital management information.
In our cohort, 29.6% of the patients were intubated. The rate of pre-hospital ETI increased with the number of indications. If only one criterion according to current guidelines was present, ETI was often omitted. In 582 patients with shock as the only indication for pre-hospital ETI, only 114 patients (19.6%) were intubated. Comparing these subgroups, the intervention was associated with longer time on scene (25.3 min vs. 41.6 min; p < 0.001), higher rate of coagulopathy (31.8% vs. 17.2%), an increased mortality (8.2% vs. 11.5%) and higher standard mortality ratio (1.17 vs. 1.35). If another intubation criterion was present in addition to shock, intubation was performed more frequently.
Decision making for pre-hospital intubation in trauma patients is challenging in front of a variety of factors. Despite the presence of a guideline recommendation, ETI is not always executed. Patients presenting with shock as remaining indication and subsequent intubation showed a decreased outcome. Thus, isolated shock does not appear to be an appropriate indication for pre-hospital ETI, but clearly remains an important surrogate of trauma severity and the need for trauma team activation.
院前气管插管(ETI)的适应证必须仔细考虑,因为它与许多风险和并发症有关。目前的指南建议,除其他外,在休克(收缩压<90mmHg)的情况下进行 ETI。本研究旨在探讨孤立性低血压而无意识丧失是否是 ETI 的有用标准。
在一项回顾性研究中,对来自创伤登记处 DGU®的 37369 名患者的数据进行了评估,研究内容为院前 ETI 和潜在的适应证。纳入标准为存在任何相关损伤(损伤严重程度评分 [AIS]≥3)和完整的院前管理信息。
在我们的队列中,有 29.6%的患者进行了插管。院前 ETI 的比率随着适应证数量的增加而增加。如果仅存在当前指南规定的一个标准,则经常会省略 ETI。在仅以休克为院前 ETI 唯一适应证的 582 名患者中,仅有 114 名患者(19.6%)进行了插管。比较这些亚组,干预与现场时间延长(25.3 分钟比 41.6 分钟;p<0.001)、凝血功能障碍发生率较高(31.8%比 17.2%)、死亡率增加(8.2%比 11.5%)和标准死亡率比增加(1.17 比 1.35)相关。如果除休克外,还存在另一个插管标准,则更频繁地进行插管。
在面对各种因素时,创伤患者院前插管的决策具有挑战性。尽管有指南推荐,但 ETI 并不总是执行。仅以休克为剩余适应证并随后进行插管的患者预后较差。因此,孤立性休克似乎不是院前 ETI 的合适适应证,但显然仍然是创伤严重程度和创伤团队激活需求的重要替代指标。