de With N D, van der Schors R C
Gen Comp Endocrinol. 1986 Sep;63(3):344-52. doi: 10.1016/0016-6480(86)90133-4.
In Lymnaea stagnalis, extirpation of the cerebral ganglia resulted in a significant decrease of the Na+ and Cl- concentrations in the haemolymph. In intact snails, injection of an extract of the cerebral ganglia stimulated the Na+ influx from the external medium in a dose-dependent way. No effect on the Cl- influx was found. Extract injections did not affect the Na+ efflux. The Na+ influx stimulating activity, in relatively high concentrations, was also present in extracts of the median lip nerve (an important neurohaemal area, originating from the cerebral ganglia). The influx-stimulating activity was heat-stable and destroyed by Pronase treatment. It is suggested that in L. stagnalis, Na+ uptake from the medium is controlled by a neurohormone produced by the cerebral ganglia.
在椎实螺中，切除脑神经节会导致血淋巴中钠离子和氯离子浓度显著降低。在完整的蜗牛中，注射脑神经节提取物会以剂量依赖的方式刺激钠离子从外部介质流入。未发现对氯离子流入有影响。提取物注射不影响钠离子流出。相对高浓度时，中唇神经（一个重要的神经血器官区域，起源于脑神经节）的提取物也具有刺激钠离子流入的活性。这种流入刺激活性对热稳定，经链霉蛋白酶处理后会被破坏。有人提出，在椎实螺中，从介质中摄取钠离子受脑神经节产生的一种神经激素控制。
