From the Baskent University, Department of General Surgery, Division of Transplantation, Ankara, Turkey.
Exp Clin Transplant. 2022 May;20(Suppl 3):85-88. doi: 10.6002/ect.PediatricSymp2022.O29.
In children with end-stage renal disease, chronic liver failure, or acute liver failure, liver transplant and kidney transplant are the most effective modalities for better clinical outcomes compared with other therapies. However, children are particularly susceptible to surgical complications, so pediatric solid-organ transplants should be reserved for centers with substantial experience and multidisciplinary expertise. Here, we assessed liver and kidney transplants performed at our center in 2021.
From November 3, 1975, to December 31, 2021, we performed 701 liver transplants and 3290 kidney transplants. From January 1, 2021, to December 31, 2021, we performed 21 liver transplants (19 in children) and 114 kidney transplants (12 in children). We recorded age, sex, body mass index, comorbidities, etiologies, laboratory values, and clinical outcomes.
For the year 2021, we performed 19 pediatric liver transplants and 12 pediatric kidney transplants. Mean age of liver recipients was 3.4 years, and 8 were male patients. The most common etiology was biliary atresia (n = 7). All liver grafts were from living related donors who were first-degree (n = 16) or second- degree (n = 3) relatives of the recipients. Mean hospital stay was 17.6 days. All but 2 liver transplant recipients were discharged successfully (2 died from sepsis in the early postoperative period). Mean age of kidney transplant recipients was 14.1 years, and 4 were male patients. The most common etiology was vesicoureteral reflux (n = 3). One kidney graft was from a deceased donor, with the rest from living related donors who were first-degree relatives of the recipients (n = 11; mother for 8 recipients and father for 3 recipients). Mean hospital stay was 4.3 days. All kidney transplant recipients were discharged successfully.
Solid-organ transplants for young children are often complex but can be performed successfully at experienced transplant centers.
在患有终末期肾病、慢性肝功能衰竭或急性肝功能衰竭的儿童中，与其他治疗方法相比，肝移植和肾移植是改善临床结局的最有效方法。然而，儿童特别容易发生手术并发症，因此儿科实体器官移植应保留给具有丰富经验和多学科专业知识的中心。在这里，我们评估了我们中心 2021 年进行的肝移植和肾移植。
从 1975 年 11 月 3 日至 2021 年 12 月 31 日，我们进行了 701 例肝移植和 3290 例肾移植。从 2021 年 1 月 1 日至 2021 年 12 月 31 日，我们进行了 21 例肝移植（19 例在儿童中）和 114 例肾移植（12 例在儿童中）。我们记录了年龄、性别、体重指数、合并症、病因、实验室值和临床结果。
在 2021 年，我们进行了 19 例儿科肝移植和 12 例儿科肾移植。肝受者的平均年龄为 3.4 岁，有 8 名男性患者。最常见的病因是胆道闭锁（n = 7）。所有肝移植物均来自活体相关供体，供体是受者的一级（n = 16）或二级（n = 3）亲属。平均住院时间为 17.6 天。除 2 例肝移植受者外，其余均成功出院（2 例因术后早期败血症死亡）。肾移植受者的平均年龄为 14.1 岁，有 4 名男性患者。最常见的病因是膀胱输尿管反流（n = 3）。1 个肾移植物来自于已故供体，其余来自活体相关供体，是受者的一级亲属（n = 11；8 个受者的母亲，3 个受者的父亲）。平均住院时间为 4.3 天。所有肾移植受者均成功出院。
对于年幼的儿童来说，实体器官移植通常很复杂，但在有经验的移植中心可以成功进行。
