Kirwan C Brock
Department of Psychology and Neuroscience Center, Brigham Young University, Provo, UT, USA.
Cogn Neurosci. 2022 Jul;13(3-4):147-148. doi: 10.1080/17588928.2022.2076073. Epub 2022 May 16.
In a clever experimental design, Tallman, Clark, and Smith (this issue) tested the changes in fMRI activation and functional connectivity in the hippocampus and cortex as a function of memory age. They found that activation changed according to a power function (both increasing and decreasing) in several cortical regions but not within the hippocampus or medial temporal lobe (MTL). Further, functional connectivity increased with memory age between cortical regions but decreased for the hippocampus. Taken together, these results offer strong support for the standard consolidation model. However, they leave open the question of what role the hippocampus plays in recognition memory performance.
在一项巧妙的实验设计中，塔尔曼、克拉克和史密斯（本期）测试了海马体和皮层中功能磁共振成像（fMRI）激活及功能连接随记忆时长的变化。他们发现，几个皮层区域的激活根据幂函数发生变化（既有增加也有减少），但海马体或内侧颞叶（MTL）内并非如此。此外，皮层区域之间的功能连接随记忆时长增加，而海马体的功能连接则减少。综合来看，这些结果为标准巩固模型提供了有力支持。然而，它们并未解决海马体在识别记忆表现中扮演何种角色这一问题。
