School of Public Health, Dalian Medical University, Dalian, Liaoning, China.
School of Traditional Chinese Medical, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
BMJ Open. 2022 May 17;12(5):e054170. doi: 10.1136/bmjopen-2021-054170.
The harm of indoor air pollution to health has gradually attracted attention, but the effect of indoor air pollution from burning solid fuels on incidental non-fatal cardiovascular disease (CVD) is not well understood. Under these circumstances, this study examined the association between solid fuel use and incidental non-fatal CVD.
The prospective cohort study was conducted in 2011, 2013, 2015 and 2018.
The nationally representative survey was conducted in 28 provinces of China.
This study included 13 544 middle-aged and elderly adults without CVD in the baseline survey, and they were followed for 7 years.
First incidence of non-fatal CVD (heart disease or stroke).
Based on longitudinal data, Cox proportional hazards models were used to assess the effects of solid fuel use and persistent use on incidental CVD events.
During the 7-year follow-up period, there were 1533 non-fatal CVD cases. A total of 7310 (54%) participants used solid fuel for cooking at the baseline survey, and 2998 (41%) users continued to use solid fuel. Solid fuel use was associated with incidental non-fatal CVD (HR: 1.18; 95% CI: 1.05 to 1.32) compared with clean fuel, and persistent solid fuel use might lead to a higher risk of incidental non-fatal CVD (HR: 1.38; 95% CI: 1.18 to 1.61) and heart disease (HR: 1.49; 95% CI: 1.24 to 1.81). In the subgroup analysis, the relationship remained significant in the female, elderly, rural and hypertensive groups. However, we found no significant interaction between these risk factors and fuel use (all p<0.05).
This cohort study provides evidence for the effects of solid fuel use on incidental non-fatal CVD in middle-aged and elderly Chinese adults. Advocating for the use of clean energy and ventilation stoves is important to cardiovascular health.
室内空气污染对健康的危害逐渐引起关注,但燃烧固体燃料对偶发性非致命性心血管疾病(CVD)的影响尚不清楚。在这种情况下,本研究调查了固体燃料使用与偶发性非致命性 CVD 之间的关联。
前瞻性队列研究于 2011 年、2013 年、2015 年和 2018 年进行。
全国代表性调查在中国 28 个省份进行。
本研究纳入了基线调查中无 CVD 的 13544 名中老年成年人,随访 7 年。
首次发生非致命性 CVD(心脏病或中风)。
基于纵向数据,使用 Cox 比例风险模型评估固体燃料使用和持续使用对偶发性 CVD 事件的影响。
在 7 年的随访期间,发生了 1533 例非致命性 CVD 病例。基线调查中,共有 7310 名(54%)参与者使用固体燃料烹饪,2998 名(41%)使用者继续使用固体燃料。与清洁燃料相比,使用固体燃料与偶发性非致命性 CVD 相关(HR:1.18;95%CI:1.05 至 1.32),持续使用固体燃料可能导致偶发性非致命性 CVD(HR:1.38;95%CI:1.18 至 1.61)和心脏病(HR:1.49;95%CI:1.24 至 1.81)的风险更高。在亚组分析中,女性、老年人、农村和高血压人群中这种关系仍然显著。然而,我们没有发现这些风险因素和燃料使用之间存在显著的交互作用(所有 p<0.05)。
本队列研究为固体燃料使用与中国中老年成年人偶发性非致命性 CVD 之间的关系提供了证据。倡导使用清洁能源和通风炉灶对心血管健康很重要。