基因治疗女性不孕：遥不可及的梦想还是现实？
Gene therapy for female infertility: A farfetched dream or reality?
机构信息
Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India.
Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India.
出版信息
Cell Rep Med. 2022 May 17;3(5):100641. doi: 10.1016/j.xcrm.2022.100641.
Abstract
A major cause of infertility in women is impaired ovulation or oogenesis. In this issue of Cell Reports Medicine, Kanatsu-Shinohara et al. demonstrate the potential of gene delivery with adeno-associated virus that can cross the blood-follicle barrier and restore oogenesis in congenitally infertile mice.
摘要
女性不孕的一个主要原因是排卵或卵子发生障碍。在本期《细胞报告医学》中，Kanatsu-Shinohara 等人证明了腺相关病毒基因传递的潜力，这种方法可以穿过血-卵泡屏障，恢复先天性不孕小鼠的卵子发生。
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