Van Horne James, Van Horne Alaine, Liao Nick, Romo-LeTourneau Victoria
Adult Reconstructive Orthopedic Surgeon, Paragon Orthopedics, Grants Pass, OR.
Clinical Research Specialist, Paragon Orthopedics, Grants Pass, OR.
Am Health Drug Benefits. 2022 Mar;15(1):21-29.
An enhanced recovery pathway using individualized multimodal pain management with scheduled nonopioid and opioid regimens previously enabled reproducible same-day discharge of Medicare beneficiaries and commercially insured patients undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA) procedures in the hospital or in ambulatory surgery center settings.
To analyze the migration trends for TKA and THA procedures from a hospital to an ambulatory surgery center facility and to assess perioperative outcomes before and after incorporating liposomal bupivacaine into a multimodal pain management regimen for these procedures.
This retrospective medical chart review study included patients undergoing THA or TKA with an enhanced recovery pathway in a hospital or an ambulatory surgery center between 2013 and 2019. The outcome measures included length of stay at the hospital or the ambulatory center, and opioid consumption. We compared the outcomes before and after the addition of liposomal bupivacaine to surgeon-applied periarticular intraoperative local anesthetic field blocks between in-hospital patients who received and patients who did not receive liposomal bupivacaine in 2013 and 2014, and the impact of liposomal bupivacaine use in the hospital versus the ambulatory center from 2015 to 2019.
In 2013 and 2014, the addition of liposomal bupivacaine increased the same-day hospital discharge rate to 32% versus 4% without liposomal bupivacaine (odds ratio, 14.3; 95% confidence interval, 5.9-33.3; <.0001); the same-day hospital discharge rates increased to 73% in 2015. From 2015 through 2019, 89% of all patients were discharged on the same day from the hospital. In-hospital opioid use was 22% lower in the liposomal bupivacaine cohort than in the patients who did not receive this medication ( = .0035). In 2018 and 2019, same-day discharge from the hospital or the ambulatory surgery center rates were 96% and 100%, respectively, and 84% of the patients used postsurgical opioid prescriptions of 30 or fewer tablets. The complication rates and healthcare resource utilization did not increase with the incorporation of liposomal bupivacaine into the enhanced recovery pathway and increased same-day discharge rates.
An enhanced recovery pathway using individualized, scheduled multimodal pain management protocol in patients undergoing THA or TKA facilitated reproducible, high same-day discharge rates and low postoperative opioid consumption. These results suggest that the use of liposomal bupivacaine for intraoperative field blocks supports predictable same-day discharge rates after THA or TKA. This protocol could facilitate same-day hospital discharge and the migration of THA and TKA procedures from the hospital to lower-cost ambulatory surgery centers.
一种采用个体化多模式疼痛管理的强化康复路径,结合预定的非阿片类和阿片类药物方案,此前已能使在医院或门诊手术中心接受全髋关节置换术(THA)或全膝关节置换术(TKA)的医疗保险受益人和商业保险患者实现可重复的当日出院。
分析TKA和THA手术从医院向门诊手术中心的转移趋势,并评估在将脂质体布比卡因纳入这些手术的多模式疼痛管理方案前后的围手术期结局。
这项回顾性病历审查研究纳入了2013年至2019年间在医院或门诊手术中心接受THA或TKA且采用强化康复路径的患者。结局指标包括在医院或门诊中心的住院时间以及阿片类药物的使用量。我们比较了2013年和2014年在接受和未接受脂质体布比卡因的住院患者中,将脂质体布比卡因添加到外科医生应用的关节周围术中局部麻醉区域阻滞前后的结局,以及2015年至2019年脂质体布比卡因在医院与门诊中心使用的影响。
在2013年和2014年,添加脂质体布比卡因使当日出院率提高到32%,而未使用脂质体布比卡因时为4%(优势比,14.3;95%置信区间,5.9 - 33.3;P <.0001);2015年当日出院率提高到73%。从2015年到2019年,所有患者中有89%在当日从医院出院。脂质体布比卡因组的住院阿片类药物使用量比未接受该药物的患者低22%(P = 0.0035)。在2018年和2019年,从医院或门诊手术中心当日出院率分别为96%和100%,并且84%的患者术后使用阿片类药物处方为30片或更少。将脂质体布比卡因纳入强化康复路径并提高当日出院率后,并发症发生率和医疗资源利用率并未增加。
在接受THA或TKA的患者中采用个体化、预定的多模式疼痛管理方案的强化康复路径有助于实现可重复的高当日出院率和低术后阿片类药物消耗量。这些结果表明,使用脂质体布比卡因进行术中区域阻滞有助于THA或TKA术后实现可预测的当日出院率。该方案可促进医院当日出院以及THA和TKA手术从医院向成本更低的门诊手术中心转移。