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来自大型糖尿病患者人群的自然毛细血管指尖血样中的氧分压分布。

Distribution of Oxygen Partial Pressures in Native Capillary Fingertip Blood Samples From a Large Diabetes Patient Population.

机构信息

LifeScan Scotland Ltd, Inverness, Highland, UK.

出版信息

J Diabetes Sci Technol. 2023 Sep;17(5):1317-1320. doi: 10.1177/19322968221095055. Epub 2022 May 19.

DOI:10.1177/19322968221095055
PMID:35587101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10563546/
Abstract

A data set comprising 28 533 oxygen partial pressure (pO) values gathered from nonarterialized fingertip capillary blood samples of a large diabetes population is reported. Data were gathered routinely as part of the ongoing clinical surveillance activities of a blood glucose monitoring (BGM) system manufacturer. Overall, a mean pO level of 75.3 mm Hg was recorded, with a standard deviation (SD) of 10.6 mm Hg and a range of 27.7 to 151.5 mm Hg. This data set, unique in terms of size, gathered more than 14 years at four separate clinical sites, provides a robust and comprehensive representation of an unmanipulated pO fingertip capillary sample distribution, which should be of interest for physiological reasons, but also from a medical device development perspective, in which the effect of pO on device performance may be an important design consideration.

摘要

本文报告了一个包含 28533 个氧分压(pO)值的数据集,这些值来自于大量糖尿病患者的非动脉化指尖毛细血管血样。这些数据是作为血糖监测(BGM)系统制造商持续临床监测活动的一部分常规收集的。总体而言,记录到的平均 pO 水平为 75.3mmHg,标准差(SD)为 10.6mmHg,范围为 27.7 至 151.5mmHg。该数据集在规模上是独一无二的,在四个不同的临床地点收集了超过 14 年的数据,为未经处理的指尖毛细血管 pO 样本分布提供了一个强大而全面的代表性,这无论出于生理原因还是从医疗器械开发的角度来看都应该是有趣的,因为 pO 对设备性能的影响可能是一个重要的设计考虑因素。

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本文引用的文献

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J Diabetes Sci Technol. 2023 Jan;17(1):133-140. doi: 10.1177/19322968211039465. Epub 2021 Aug 31.
2
Global and country-level estimates of human population at high altitude.全球和国家层面的高海拔地区人口估计数。
Proc Natl Acad Sci U S A. 2021 May 4;118(18). doi: 10.1073/pnas.2102463118.
3
Agreement between arterial and non-arterialised fingertip capillary blood gas and acid-base values.动脉血与非动脉化指尖毛细血管血气及酸碱值之间的一致性。
Eur Clin Respir J. 2019 Jul 25;6(1):1644892. doi: 10.1080/20018525.2019.1644892. eCollection 2019.
4
Evidence From a Long-Term, Systematic Post-Market Surveillance Program: Clinical Performance of a Hematocrit-Insensitive Blood Glucose Test Strip.长期、系统的上市后监测计划的证据:一种红细胞压积不敏感的血糖测试条的临床性能。
J Diabetes Sci Technol. 2021 Jan;15(1):67-75. doi: 10.1177/1932296819826968. Epub 2019 Feb 7.
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Seven-Year Clinical Surveillance Program Demonstrates Consistent MARD Accuracy Performance of a Blood Glucose Test Strip.七年临床监测项目证明血糖测试条的平均相对偏差(MARD)准确性表现稳定。
J Diabetes Sci Technol. 2018 Sep;12(5):1016-1023. doi: 10.1177/1932296818776668. Epub 2018 May 30.
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Seven-Year Surveillance of the Clinical Performance of a Blood Glucose Test Strip Product.血糖试纸产品七年临床性能监测
J Diabetes Sci Technol. 2017 Nov;11(6):1155-1162. doi: 10.1177/1932296817703133. Epub 2017 Apr 13.
7
Relating oxygen partial pressure, saturation and content: the haemoglobin-oxygen dissociation curve.关联氧分压、饱和度与含量:血红蛋白-氧解离曲线
Breathe (Sheff). 2015 Sep;11(3):194-201. doi: 10.1183/20734735.001415.
8
Partial pressure of oxygen in capillary blood samples from the fingertip.来自指尖的毛细血管血样中的氧分压。
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9
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J Diabetes Sci Technol. 2013 Nov 1;7(6):1513-21. doi: 10.1177/193229681300700611.
10
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