Avgeri Theodora-Carolina, Sideris Giorgos, Maragoudakis Pavlos, Papadopoulos Iordanis, Nikolopoulos Thomas, Delides Alexander
National & Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, 2nd Otolaryngology Department, Athens, Greece.
National & Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, 4th Department of Surgery, Athens, Greece.
J Taibah Univ Med Sci. 2021 Aug 28;17(2):214-219. doi: 10.1016/j.jtumed.2021.08.001. eCollection 2022 Apr.
Hypocalcaemia and hypoparathyroidism are the most frequent complications of total thyroidectomy that may result in the need for lifelong calcium supplementation. This study aims to investigate the impact of incidental parathyroidectomy on short- and long-term hypocalcaemia.
This retrospective study was conducted on patients who underwent total thyroidectomy with or without central neck dissection between March 2016 to May 2018. All procedures were performed by three surgeons with similar experience levels. Histopathology reports were reviewed, the number of resected parathyroid glands and the underlying pathology reports were recorded, and the patients were divided into two groups; groups A and B comprised those with and without parathyroid glands respectively. The incidence rates of short- and long-term hypocalcaemia were recorded. The former was obtained through blood tests during hospitalisation and the latter via phone calls to patients 3, 6, and 12 months postoperatively.
A total of 116 patients participated, 18 (15.5%) in group A and 98 (84.5%) in group B. No statistical significance was detected between the two groups regarding early postoperative ( = 0.109) or long-term hypocalcaemia ( = 0.48). These results were similar in patients with cancer (n = 40) ( = 0.855, = 0.08).
Incidental parathyroidectomy of one parathyroid gland was not correlated with a higher incidence of hypocalcaemia, even in cases with thyroid cancer.
低钙血症和甲状旁腺功能减退是全甲状腺切除术后最常见的并发症，可能需要终身补钙。本研究旨在探讨意外甲状旁腺切除术对短期和长期低钙血症的影响。
本回顾性研究针对2016年3月至2018年5月期间接受全甲状腺切除术（无论是否行中央区淋巴结清扫）的患者进行。所有手术均由三名经验水平相近的外科医生完成。回顾组织病理学报告，记录切除甲状旁腺的数量及基础病理报告，并将患者分为两组；A组和B组分别为有甲状旁腺和无甲状旁腺的患者。记录短期和长期低钙血症的发生率。前者通过住院期间的血液检查获得，后者通过术后3、6和12个月给患者打电话获得。
共有116例患者参与，A组18例（15.5%），B组98例（84.5%）。两组在术后早期（P = 0.109）或长期低钙血症方面均未检测到统计学差异（P = 0.48）。癌症患者（n = 40）的结果相似（P = 0.855，P = 0.08）。
即使在甲状腺癌病例中，意外切除一个甲状旁腺与低钙血症的较高发生率也无相关性。
