Koresawa M, Inaba J, Iwasaki H
Nihon Sanka Fujinka Gakkai Zasshi. 1987 Mar;39(3):395-9.
Fetal blood sampling has been performed in several ways; placentacentesis, fetoscopy, or umbilical code puncture. The problems with these methods are technical difficulties and contamination of maternal blood or amniotic fluid. To solve these problems, we have tried fetal blood sampling by fetal liver puncture with a 21 approximately 23 gauge needle through the maternal abdomen under real time scan guidance. 10 patients underwent this procedure. They ranged from 18 weeks to 22 weeks of gestation at the time of sampling. The sampling procedures were done easily and the samples taken were shown to be pure fetal blood by red blood cell sizing. All the patients continued pregnancy after the examination and none of the pregnancies was influenced by the puncture. 7 patients have been delivered with neither sampling scars nor damage to liver function. This method provides pure fetal blood, the procedure is simple and, in our experience, no complications have occurred.
胎儿血样采集有多种方式,如胎盘穿刺术、胎儿镜检查或脐静脉穿刺术。这些方法存在技术难题以及母体血液或羊水污染的问题。为解决这些问题,我们尝试在实时扫描引导下,经母体腹部用21至23号针进行胎儿肝穿刺采集胎儿血样。10例患者接受了该操作。采样时,她们的孕周在18至22周之间。采样过程轻松完成,通过红细胞大小测定显示所采集的样本为纯胎儿血。所有患者检查后继续妊娠,且无一例妊娠受穿刺影响。7例患者已分娩,既无采样疤痕,肝功能也未受损。该方法可获取纯胎儿血,操作简单,且根据我们的经验,未发生并发症。