阿联酋心血管危险因素流行状况及冠心病 10 年发病风险
Prevalence of Cardiovascular Risk Factors and 10-Years Risk for Coronary Heart Disease in the United Arab Emirates.
机构信息
Department of Cardiology, Burjeel Royal Hospital, Al-Ain, UAE.
Department of Cardiology, Kids, and Adult Heart Centers Dubai and Abu Dhabi, Dhabi, UAE.
出版信息
Curr Diabetes Rev. 2023;19(3):e210422203892. doi: 10.2174/1573399818666220421113607.
BACKGROUND
In the United Arab Emirates (UAE), cardiovascular diseases (CVDs) are the leading cause of mortality, and the incidence of premature coronary heart diseases (CHDs) is about 10-15 years earlier than that in people of western countries.
AIM
The current cross-sectional study aims to describe the prevalence of CVD risk factors and estimate the 10-years risk for CHDs in the population of Abu Dhabi, UAE.
OBJECTIVE
The main objective was to report the 10-years risk for CHD in a sample of the UAE population.
METHODS
We have analyzed the dataset from the Abu Dhabi Screening Program for Cardiovascular Risk Markers (AD-SALAMA), a population-based cross-sectional survey conducted between 2009 and 2015 (a sample of 1002, 20 to 79 years old without CVDs or diabetes).
RESULTS
18.0% of our sample have had hypertension (HTN), 26.3% were current smokers, 33% have had total cholesterol ≥200 mg/dL, 55.0% have had non-high-density lipoprotein (non-HDL) levels ≥130 mg/dL, 33.1% have had low-density lipoprotein cholesterol (LDL-C) levels ≥130 mg/dL, calculated by β-quantification as 112.3 ± 47.1 mg/dL. 66.8% were overweight or obese, and 46.2% had a sedentary lifestyle. Nearly 85% of our sample has had one or more major cardiovascular risk factors. The estimated 10-year risk of cardiovascular disease according to different risk assessment tools was as follows: 7.1% according to the national cholesterol education program Framingham risk score (FRAM-ATP), 2.9% according to Pooled Cohort Risk Assessment Equation (PCRAE) , 1.4% according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III), and 1.1% according to Reynolds Risk Score. Despite the fact that our sample population have had exhibited major risk factors, the above-mentioned international scoring systems underestimate the 10-year risk of cardiovascular diseases, given the high prevalence at younger ages.
CONCLUSION
The proportion of modifiable risk factors has been found to be high in the UAE population, and the majority of them have had one or more risk factors with a higher 10-years risk for CHDs.
背景
在阿拉伯联合酋长国（阿联酋），心血管疾病（CVDs）是导致死亡的主要原因，且早发性冠心病（CHD）的发病率比西方国家早 10-15 年。
目的
本横断面研究旨在描述 CVD 危险因素的流行情况，并评估阿联酋阿布扎比人群患 CHD 的 10 年风险。
目标
主要目的是报告阿联酋人群的 CHD 10 年风险。
方法
我们分析了阿布扎比心血管风险标志物筛查计划（AD-SALAMA）的数据，该计划是一项基于人群的横断面调查，于 2009 年至 2015 年进行（样本为 1002 名年龄在 20-79 岁、无 CVD 或糖尿病的人群）。
结果
我们的样本中有 18.0%患有高血压（HTN），26.3%是当前吸烟者，33%的总胆固醇≥200mg/dL，55.0%的非高密度脂蛋白（non-HDL）水平≥130mg/dL，33.1%的 LDL-C 水平≥130mg/dL，通过β定量计算为 112.3±47.1mg/dL。66.8%超重或肥胖，46.2%有久坐的生活方式。我们的样本中几乎有 85%的人有一个或多个主要心血管危险因素。根据不同的风险评估工具，估计的 10 年心血管疾病风险如下：根据国家胆固醇教育计划 Framingham 风险评分（FRAM-ATP）为 7.1%，根据 Pooled Cohort Risk Assessment Equation（PCRAE）为 2.9%，根据国家胆固醇教育计划成人治疗小组 III（NCEP ATP III）为 1.4%，根据 Reynolds 风险评分（Reynolds Risk Score）为 1.1%。尽管我们的样本人群存在主要危险因素，但由于年龄较小，上述国际评分系统低估了心血管疾病的 10 年风险。
结论
阿联酋人口中可改变的危险因素比例较高，大多数人有一个或多个危险因素，患 CHD 的 10 年风险较高。
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