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[骨糊和生物活性玻璃颗粒在胆脂瘤手术中用于乳突填充的应用]

[Use of bone pate and bioactive glass granules for mastoid obliteration in cholesteatoma surgery].

作者信息

Gerlinger Imre, Szabó Éva, Szanyi István, Rostás Tamás, Pap István, Révész Péter, Kopjár Eszter

机构信息

1 Pécsi Tudományegyetem, Általános Orvostudományi Kar, Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika Pécs, Munkácsy M. u. 2., 7621 Magyarország.

2 Pécsi Tudományegyetem, Általános Orvostudományi Kar, Orvosi Képalkotó Klinika Pécs Magyarország.

出版信息

Orv Hetil. 2022 May 22;163(21):838-845. doi: 10.1556/650.2022.32477.

Abstract

Introduction and objective: Mastoid obliteration technique combines the advantages of canal wall-up (CWU) and canal wall-down (CWD) approaches in the surgery of chronic suppurative otitis media with cholesteatoma. We aim to demonstrate our experience with mastoid obliteration technique using bone dust and BonAlive® (S53P4) bioactive glass granule in a comparative prospective clinical study. Patients and methods: Between 1st of March 2012 and 31st of November 2021, mastoid obliteration surgery was performed in 14 patients using bone dust (7 cases) and BonAlive® granule (7 cases). Prior to these interventions, the patients had undergone more than three ear surgeries (CWU and CWD) generally in both groups. Changes of complaints, audiological results, and changes in quality of life were analysed in both groups, postoperatively. Results: Having performed the mastoid obliteration technique, cochlear damage did not occur in either patient group. Long-term ear discharge and vertigo were occasionally observed after performing obliteration with bone dust. However, these complaints disappeared after a while. Complications were not reported in the case of obliteration with BonAlive®. Outstanding improvement was experienced in both groups. Conclusion: In our practice, mastoid obliteration surgery, using either bone dust or BonAlive® granule, has proved to

摘要

引言与目的

乳突封闭技术结合了上鼓室开放(CWU)和下鼓室开放(CWD)两种术式在慢性化脓性中耳炎伴胆脂瘤手术中的优势。我们旨在通过一项比较性前瞻性临床研究,展示使用骨粉和BonAlive®(S53P4)生物活性玻璃颗粒进行乳突封闭技术的经验。患者与方法:2012年3月1日至2021年11月31日期间,对14例患者进行了乳突封闭手术,其中7例使用骨粉,7例使用BonAlive®颗粒。在这些干预措施之前,两组患者一般都接受过三次以上的耳部手术(CWU和CWD)。术后分析了两组患者的症状变化、听力学结果以及生活质量变化。结果:采用乳突封闭技术后,两组患者均未发生耳蜗损伤。使用骨粉进行封闭后,偶尔会观察到长期耳漏和眩晕。然而,这些症状过一段时间后消失了。使用BonAlive®进行封闭未报告并发症。两组均有显著改善。结论:在我们的实践中,使用骨粉或BonAlive®颗粒进行乳突封闭手术已被证明…… (原文此处似乎不完整)

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