Oliverio Giovanni William, Tedesco Giovanni Roberto, Azzaro Claudia, Meduri Alessandro, Aragona Pasquale
Bioscenses Departement, Ophthalmology Clinic, University of Messina, Messina, Italy.
Studio Oculistica Tedesco, Girifalco, Italy.
Case Rep Ophthalmol. 2022 Mar 21;13(1):204-209. doi: 10.1159/000523732. eCollection 2022 Jan-Apr.
Choroidal metastases from breast cancer are the most common ocular malignancies in adults. We report a case of a 37-year-old female with a history of breast cancer who had a sudden blurred vision in her right eye. An ophthalmologic assessment revealed a dome-shaped lesion and a secondary retinal detachment with subretinal fluid in the left eye, suggestive of choroidal metastasis. Moreover, an MRI scan showed the presence of a single brain lesion. The patient was treated with stereotactic radiotherapy, with 300 cGy for 10 days. Six months after treatment, there was a regression of the mass and improvement of visual acuity. Stereotactic radiotherapy is a safe and effective treatment for choroidal metastases and should be considered to treat coexistent choroidal and brain metastatic lesions, to improve survival, visual function, and quality of life.
乳腺癌的脉络膜转移是成人中最常见的眼部恶性肿瘤。我们报告一例37岁有乳腺癌病史的女性,其右眼突然视力模糊。眼科检查发现左眼有一个穹窿状病变及继发性视网膜脱离伴视网膜下液,提示脉络膜转移。此外,磁共振成像扫描显示有单个脑转移瘤。该患者接受了立体定向放射治疗,剂量为300厘戈瑞,共10天。治疗6个月后,肿块缩小,视力改善。立体定向放射治疗是治疗脉络膜转移的一种安全有效的方法,对于同时存在的脉络膜和脑转移瘤应考虑采用该方法治疗,以提高生存率、视觉功能和生活质量。