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以口腔肉芽肿为首发症状的嗜酸性肉芽肿性多血管炎:一例报告

Eosinophilic Granulomatosis With Polyangiitis Presenting With Oral Granuloma as the Initial Symptom: A Case Report.

作者信息

Lin Lirong, Yu Rongjie, Zheng Luquan, Gong Shuyu, Yang Jurong

机构信息

Department of Nephrology, The Third Affiliated Hospital of Chongqing Medical University (General Hospital), Chongqing, China.

出版信息

Front Med (Lausanne). 2022 May 10;9:842137. doi: 10.3389/fmed.2022.842137. eCollection 2022.

Abstract

Antineutrophil cytoplasmic antibody associated vasculitis includes granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis. While EGPA has no specific symptoms, it usually presents as necrotizing vasculitis, eosinophil infiltration of the tissues and organs, and extravascular granuloma formation. Here, we report a patient who had a rare initial presentation of oral granuloma and had been previously misdiagnosed several times at other hospitals. He was finally diagnosed with EGPA and recovered after methylprednisolone and cyclophosphamide treatment. The disease EGPA can present with a rare initial presentation of oral granuloma, methylprednisolone, and cyclophosphamide can be a suitable choice of treatment.

摘要

抗中性粒细胞胞浆抗体相关性血管炎包括肉芽肿性多血管炎、嗜酸性肉芽肿性多血管炎(EGPA)和显微镜下多血管炎。虽然EGPA没有特异性症状,但通常表现为坏死性血管炎、组织和器官的嗜酸性粒细胞浸润以及血管外肉芽肿形成。在此,我们报告一名患者,其最初表现为罕见的口腔肉芽肿,此前在其他医院曾被误诊多次。他最终被诊断为EGPA,经甲泼尼龙和环磷酰胺治疗后康复。EGPA疾病可表现为罕见的口腔肉芽肿初始表现,甲泼尼龙和环磷酰胺可能是合适的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44a2/9129884/86e1a8e9e215/fmed-09-842137-g0001.jpg

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