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老年主动脉瓣狭窄患者经导管主动脉瓣置换术治疗目标的观点。

Elderly aortic stenosis patients' perspectives on treatment goals in transcatheter aortic valvular replacement.

机构信息

Division of Cardiology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

Department of Cardiovascular Medicine, Kyorin University Faculty of Medicine, Tokyo, Japan.

出版信息

ESC Heart Fail. 2022 Aug;9(4):2695-2702. doi: 10.1002/ehf2.14008. Epub 2022 Jun 8.

Abstract

AIMS

Transcatheter aortic valvular replacement (TAVR) is increasingly being performed for elderly patients with aortic stenosis (AS), and current guidelines acknowledge the importance of shared decision-making in their management. This study aimed to evaluate elderly symptomatic severe AS patients' perspectives on their treatment goals and identify factors that influence their treatment choice.

METHODS AND RESULTS

We performed a pre-procedural cross-sectional survey using a questionnaire at a single university hospital. The questionnaire included three primary domains: (i) symptom burden, (ii) goals and important factors related to treatment, and (iii) preferred place of residence after treatment. We investigated 98 symptomatic severe AS patients who underwent TAVR (median age 86 years, 26% men). None of the patients died during hospitalization, and most of them (94%) were discharged home. Prior to TAVR, the three most common symptom burdens were poor mobility (52%), shortness of breath (52%), and weakness (44%). The reported preferred treatment goals were symptom burden reduction (78%), independence maintenance (68%), ability to perform a specific activity/hobby (62%), and improvement in prognosis (58%). In total, 54% of the patients rated 'in alignment with my values' as the factor that affected their decision to undergo TAVR. Nearly all patients (95%) stated that they preferred to live at home after TAVR.

CONCLUSIONS

Among elderly AS patients with varying symptoms who underwent TAVR, symptom burden reduction was the most cited patient-reported goal. Nearly all the patients preferred to live at home after the procedure. Encouraging patients to define their specific goals may improve the quality of shared decision-making in such settings.

摘要

目的

经导管主动脉瓣置换术(TAVR)越来越多地用于治疗老年主动脉瓣狭窄(AS)患者,目前的指南承认在其治疗管理中共同决策的重要性。本研究旨在评估老年有症状的重度 AS 患者对其治疗目标的看法,并确定影响其治疗选择的因素。

方法和结果

我们在一家大学医院进行了一项术前横断面调查,使用问卷进行。问卷包括三个主要领域:(i)症状负担,(ii)与治疗相关的目标和重要因素,(iii)治疗后首选的居住地。我们调查了 98 名接受 TAVR 的有症状的重度 AS 患者(中位年龄 86 岁,26%为男性)。在住院期间,没有患者死亡,大多数患者(94%)出院回家。在 TAVR 之前,最常见的三种症状负担是行动不便(52%)、呼吸困难(52%)和虚弱(44%)。报告的首选治疗目标是减轻症状负担(78%)、维持独立性(68%)、进行特定活动/爱好的能力(62%)和改善预后(58%)。共有 54%的患者将“与我的价值观一致”评为影响他们接受 TAVR 决策的因素。几乎所有患者(95%)表示,他们希望在 TAVR 后居住在自己家中。

结论

在接受 TAVR 的有不同症状的老年 AS 患者中,减轻症状负担是患者报告的最常见目标。几乎所有患者都希望在手术后居住在自己家中。鼓励患者定义其特定目标可能会提高此类情况下共同决策的质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c13/9288810/1e695edf1323/EHF2-9-2695-g003.jpg

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